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003 EG-GiCUC
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008 200906s2020 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.10.Ph.D.2020.Yo.A
100 0 _aYousra Abdulsalam Muhammad Hasan Azzazi
245 1 0 _aAssessment of atherosclerotic cardiovascular risk and oxidative stress in vitiligo :
_bA case control study /
_cYousra Abdulsalam Muhammad Hasan Azzazi ; Supervised Wedad Zoheir Mostafa , Khadiga Sayed Sayed , Nanis Abdelaleem Ragab
246 1 5 _aتقييم مخاطر إصابة القلب و الأوعية الدموية بتصلب الشرايين المرتبط بالإجهاد التأكسدى فى مرضى البهاق :
_bدراسة للحالات و الشواهد
260 _aCairo :
_bYousra Abdulsalam Muhammad Hasan Azzazi ,
_c2020
300 _a134 , (12) P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology
520 _aBackground:Vitiligo is a relatively common skin depigmenting disorder, of multifactorial etiology including genetic, immunologicaland oxidant-antioxidant imbalance.Nonsegmental vitiligo, the commonest form of vitiligo, is now postulated to be a systemic disease, rather than a mere dermatological disorder, having a strong association with several systemic and metabolic disturbances, including insulin resistance, dyslipidemia, atherosclerotic cardiovascular disease (CVD) and metabolic syndrome. However, contradicting data were also published, denoting that vitiligo patients tend to have lower cardiovascular risk than controls. Methods:In this hospital based, cross sectional, case-control study, 50 patients with non-segmental vitiligo and 50 age and sex matched controls were included. All study subjects were selected from non-smoking subjects, free from diabetes mellitus, hypertension and obesity. Serum lipid profile (including LDL-C, HDL-C, total cholesteroland triglycerides),in addition to serum oxidative stress biomarkers (hydrogen peroxide, malondialdehyde, nitric oxide and total antioxidant capacity) were measured. Carotid duplexwas performedwithestimation of common carotid intima media thickness (CCIMT) and assessment for atherosclerotic plaque presence and measurements
530 _aIssued also as CD
653 4 _aAtherosclerosis
653 4 _aCarotid intima media thickness
653 4 _aLipid profile
700 0 _aKhadiga Sayed Sayed ,
_eSupervisor
700 0 _aNanis Abdelaleem Ragab ,
_eSupervisor
700 0 _aWedad Zoheir Mostafa ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c77593
_d77593