| 000 | 02861cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032608.0 | ||
| 008 | 201004s2019 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.11.28.Ph.D.2019.Sa.D | ||
| 100 | 0 | _aSarah Ali Adel Mohamed Elsaid | |
| 245 | 1 | 0 |
_aDiagnostic value of neutrophil CD64, CD11b and hematological scoring system in neonatal sepsis / _cSarah Ali Adel Mohamed Elsaid ; Supervised Khaled Mohamed Salama , Ismail Bahey Eldin Elhawary , Rania Mohamed Samy |
| 246 | 1 | 5 | _aفى خلايا الدم البيضاء ونظام حساب معاملات صورة الدم فى حالات تلوث الدم فى حديثى الولادة CD64 & CD11b القيمة التشخيصية لقياس معاملى |
| 260 |
_aCairo : _bSarah Ali Adel Mohamed Elsaid , _c2019 |
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| 300 |
_a162 P. : _bcharts , facimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics | ||
| 520 | _aIntroduction;2Suspected sepsis3 is one of the most frequently challenging diagnosisin neonates, the clinical signs of infection are not specific and late. Blood culture - the golden standard in neonatal sepsis diagnosis {u2013} provides late information.Aim of work ;Evaluation of Rodwell score efficiency and CD64 and CD11b expression in cases with culture proven sepsis. Patients and methods;107 patients with culture proven sepsis were examined for monocytic and neutrophilic CD11b and CD64 expressions analyzed by flowcytometry, and their CBC was analyzed and Rodwell score was calculated.Results; CD64 on both monocytes and neutrophils weresignificantly higher among patients with culture proven sepsis than that in control group with (P< 0.001) for both with sensitivity of 94.9% and 76.2%, and specificity of 59% and 83% respectively., while there was no significant different for CD11b on both monocytes and neutrophils between cases and control groups.We also found that Rodwell score was significantly higher in cases than the control group with (P<0.001) with sensitivity of 87.85% and specificity of 94%.Conclusion; that HSS is a simple screening test for early diagnosis of neonatal sepsis. It may aid the clinicians in identifying sepsis and to institute proper anti-biotic therapy. Unnecessary exposure of infants to antibiotic therapy can thus be avoided | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aCD11b | |
| 653 | 4 | _aCD64 | |
| 653 | 4 | _aHematological scoring system (HSS) | |
| 700 | 0 |
_aIsmail Bahey Eldin Elhawary , _eSupervisor |
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| 700 | 0 |
_aKhaled Mohamed Salama , _eSupervisor |
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| 700 | 0 |
_aRania Mohamed Samy , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c78052 _d78052 |
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