| 000 | 02380cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032609.0 | ||
| 008 | 201006s2020 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.10.17.M.Sc.2020.Sh.P | ||
| 100 | 0 | _aShourok Essam Aly Abdelhady | |
| 245 | 1 | 0 |
_aProcess development of nano-aluminum hydroxide adjuvanted rift valley fever virus vaccine / _cShourok Essam Aly Abdelhady ; Supervised Mohamed A. Shalaby , Ausama A. Yousif , Karim Eldin Zaki |
| 246 | 1 | 5 | _aتطوير العمليات لإنتاج لقاح لفيروس حمى الوادي المتصدع مُساعد بمادة هدروكسيد الألومنيوم متناهى الصغر |
| 260 |
_aCairo : _bShourok Essam Aly Abdelhady , _c2020 |
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| 300 |
_a96 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Virology | ||
| 520 | _aIn this study the aluminum hydroxide adjuvant gel used widely in a lot of human and animal vaccines and currently solely used as an adjuvant in the locally produced inactivated Rift Valley Fever vaccine was treated by ultrasonication in the presence of trehalose for dispersion of its particles. The dispersed aluminum hydroxide adjuvant was extensively studied where various physical characters were determined. The particle size of aluminum hydroxide was significantly reduced as the aggregates size ranging from 1-20 æm. As a result of dispersion, the TEM image of vaccine showed a change of the content from nonuniform and large aggregates of aluminum hydroxide with Rift Valley fever inactivated virus diffused in it to uniform particles with aluminum hydroxide adsorbed on virus surface and having a diameter of 300 nm. The vaccine with dispersed aluminum hydroxide was used in immunizing mice and showed superiority in immunogenicity when compared to the conventional vaccine | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aAluminum hydroxide | |
| 653 | 4 | _aNano | |
| 653 | 4 | _aRVF | |
| 700 | 0 |
_aAusama A. Yousif , _eSupervisor |
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| 700 | 0 |
_aKarim Eldin Zaki , _eSupervisor |
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| 700 | 0 |
_aMohamed A. Shalaby , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c78098 _d78098 |
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