000			03174cam a2200349 a 4500
003			EG-GiCUC
005			20250223032610.0
008			201007s2020 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.28.M.Sc.2020.To.I
100	0		_aToka Emad Eldin Saad Ibrahim
245	1	0	_aImpulse oscillometry and spirometry in transfusion dependent and non-transfusion dependent beta-thalassemia pediatric patients / _cToka Emad Eldin Saad Ibrahim ; Supervised Mona Hassan Altagui , Christine William Shaker Basanti , Mai Mohamed Mohamed Abdalsalam
246	1	5	_aقياس الذبذبات و قياس التنفس الدافع في الاطفال المرضي بأنيميا البحر المتوسط المعتمدين علي نقل الدم و الغير معتمدين
260			_aCairo : _bToka Emad Eldin Saad Ibrahim , _c2020
300			_a124 P. : _bcharts , facsmilies ; _c30cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520			_aBeta-thalassemia is an inherited hemoglobin disorder characterized by failure of the patient to produce beta hemoglobin chains, usually resulting in severe anemia in its homozygous and compound heterozygous forms.the use of regular and frequent blood transfusions in patients with Beta-thalassemia major has improved patients{u2019} life span and quality of life but can lead to chronic iron overload. Many of the complications of Beta-thalassemia result from iron deposition in the heart, endocrine glands and lungs. Although pulmonary dysfunction is not the most significant clinical manifestation of thalassemia, a certain reduction of pulmonary functions has been reported to occur in most subjects with beta thalassemia. So, we aimed in our study to determine the pattern of pulmonary dysfunction in ß-thalassemia children and to detect possible associated factors. Sixty ß-thalassemia patients were assessed for evaluation of pulmonary complications through detailed history taking, clinical examination and pulmonary function tests (Spirometry and Impulse oscillometry). Total of sixty children were included 53.3 % were females and 46.7% were males (with mean age of 10.6±3.5 years).By spirometry, 50% of patients showed restrictive lung disease, 15% of patients showed small air way obstruction and 35% of patients showed normal pattern. By impulse oscillometry, 35% of patients showed abnormal findings. Only 28.3% of patients showed abnormal findings in both spirometry and impulse oscillometry. Age was positively correlated to pulmonary dysfunction and no correlation was found between serum ferritin and pulmonary dysfunction
530			_aIssued also as CD
653		4	_aImpulse oscillometry
653		4	_aSerum ferritin
653		4	_aSpirometry
700	0		_aChristine William Shaker Basanti , _eSupervisor
700	0		_aMai Mohamed Mohamed Abdalsalam , _eSupervisor
700	0		_aMona Hassan Altagui , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aAmira _eCataloger
905			_aNazla _eRevisor
942			_2ddc _cTH
999			_c78120 _d78120