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003 EG-GiCUC
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008 201101s2020 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.36.M.Sc.2020.Re.E
100 0 _aReem Mahmoud Mohamed Ali Gabr
245 1 0 _aElectrophysiological evaluation of motor unit dysfunction in liver cirrhotic patients /
_cReem Mahmoud Mohamed Ali Gabr ; Supervised Saly Hassan Elkholy , Mye Ali Basheer , Marwa Khairy Mehssab
246 1 5 _aتقييم الوظيفه الحركيه لمرضى تليف الكبد باستخدام رسم و تخطيط الأعصاب و العضلات
260 _aCairo :
_bReem Mahmoud Mohamed Ali Gabr ,
_c2020
300 _a121 P. :
_bcharts , facimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Neurophysiology
520 _aBack ground: Liver cirrhosis is a global health problem which could be associated with several neurological manifestations.Numbness,fatigue and muscle cramps are frequently complaining symptoms in these patients. Objective: Early detection of peripheral neuropathy and loss of motor units, among patients of liver cirrhosis by motor unit number estimation (MUNE).In addition, finding out correlation between peripheral neuropathy and severity of the liver cirrhosis. Methods: This cross-sectional study conducted on fifty-six liver cirrhotic patients (Group-1), and sixty-one age/gender matched healthy controls (Group-2). The recruited patients were clinically assessed. For all the allocated cirrhotic patients, conventional nerve conduction studies (NCS) as well as quantitative electromyography (Q-EMG) were performed.Interference pattern analysis (IPA) and MUNE were the Q-EMG techniques studied. Results: Liver cirrhosis wassecondary to Hepatitis 2C3 viral (HCV) infection in (80.3%) of the patients.Most of the liver cirrhotic patients were classified as Child-Pugh 2A3 class (62.5%).The most common encountered symptoms by the patients were muscle cramps (64.3%) and fatigue (35.7%). Group-1 was further subdivided into two subgroups; depending on their manifestations; manifested (Group-1A) which included 80.4% of studied patients, and non-manifested (Group-1B), includedthe remaining 19.6% of allocated patients. 28.6% of the studied cases had peripheral neuropathy by nerve conduction studies, that was significantly correlated to Child-Pugh classification (p-value <0.001) as well as (Model for End Stage Liver Disease) MELD score (P-value= 0.014)
530 _aIssued also as CD
653 4 _aChild-Pugh
653 4 _aHepatitis 2C3 Virus (HCV)
653 4 _aInterference Pattern Analysis (IPA)
700 0 _aMarwa Khairy Mehssab ,
_eSupervisor
700 0 _aMye Ali Basheer ,
_eSupervisor
700 0 _aSaly Hassan Elkholy ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c78507
_d78507