000			03144cam a2200337 a 4500
003			EG-GiCUC
005			20250223032642.0
008			201206s2020 ua dhb f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.07.06.M.Sc.2020.El.C
100	0		_aElkotb Mohamed Ibrahim Elhananfi
245	1	0	_aCyanobacteria as biopharmaceutical producers / _cElkotb Mohamed Ibrahim Elhananfi ; Supervised Waleed Diaeddeen saleh , Mona Hussein Badawi
246	1	5	_aالسيانوبكتيريا كمنتج حيوى للعقاقير الطبية
260			_aCairo : _bElkotb Mohamed Ibrahim Elhananfi , _c2020
300			_a137 P . : _bcharts , facsmilies , maps ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Agriculture - Department of Microbiology
520			_aCyanobacteria constitute a vast potential resource in various applications such as pharmaceutical, agriculture, food, feed, fuel, fertilizer, industry and in combating pollution. In this study, the biodiversity of aquatic cyanobacteria was monitored in various water resources representing those of the River Nile at Giza and Ain Sokhna, Red sea in Egypt as well as some United Arab Emirates water supplies. Total number of six isolates were secured and subjected for morphological and microscopic examinations. Three isolates representing the most common members were identified using the molecular biology techniques. Those were closely related to the genera Anabaena sp., Oscillatoria sp. and Synechocystis sp. of the Gene Bank. They were evaluated for their potential capacities as anti-fungal and anti-bacterial agents as well as measuring their anti-oxidant activities. The examinations of hexane, methanol, chloroform and diethyl extracts of the tested cyanobacterial cultures indicated the presence of several metabolites including 9-hexadecenoic acid, leukotriene C4, neophytadiene, phthalic acid, hexadecanoic acid, octadecenoic acid, octasiloxane hexadecamethyl, phytol acetate, octadecadienoyl chloride and cyclohexasiloxane dodecamethyl. Adopting the disk diffusion method, the cyanobacterial extracts as anti-bacterial substances arranged the examined cultures in the descending order of Anabaena > Synechocystis > Oscillatoria with inhibition zone averages of 11.3, 10.7 and 10.3 mm, respectively. Similarly, the experimented microbiota considerably varied in their anti-fungal capabilities where the cyanobacterium Anabaena seemed the most active one. In respect to the anti-oxidant activity, Oscillatoria was the pioneer among the other tested ones. All in all, this study supports the applicability of such very unique aquatic creatures in the biotechnological approaches and pharmaceutical ones in particular
530			_aIssued also as CD
653		4	_aAnabaena
653		4	_aOscillatoria
653		4	_aSynechocystis
700	0		_aMona Hussein Badawi , _eSupervisor
700	0		_aWaleed Diaeddeen Saleh , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aAmira _eCataloger
905			_aNazla _eRevisor
942			_2ddc _cTH
999			_c79152 _d79152