000 | 02367cam a2200325 a 4500 | ||
---|---|---|---|
003 | EG-GiCUC | ||
008 | 201216s2020 ua d f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
||
041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aPh.D | ||
099 | _aCai01.08.08.Ph.D.2020.Yo.N | ||
100 | 0 | _aYoussef Ahmed Youssef Elsherif | |
245 | 1 | 0 |
_aNanoparticles as an oral drug delivery system for certain drug / _cYoussef Ahmed Youssef Elsherif ; Supervised Mohamed Aly Kassem , Magdy Ibrahim Mohamed , Fathy Ibrahim Abdallah |
246 | 1 | 5 | _aالجسيمات متناهية الصغر كنظام توصيل فموى لعقار معين |
260 |
_aCairo : _bYoussef Ahmed Youssef Elsherif , _c2020 |
||
300 |
_a156 P. : _bcharts , facsimiles ; _c25cm |
||
502 | _aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics | ||
520 | _aOxybutynin chloride is the gold first line treatment of nocturnal enuresis, oxybutynin chloride acts as a competitive antagonist of acetylcholine at postganglionic muscarinic receptors, resulting in relaxation of bladder smooth muscle. Although oxybutynin chloride is active, the drug bioavailability is only 6%. If the bioavailability of oxybutynin chloride is increased, this may increase the advantage of this important drug.The work in this thesis is divided into three parts: Part I: Formulation and evaluation of oxybutynin chloride nanosponge. Chapter I: Formulation and evaluation of oxybutynin chloride nanosponge by solvent evaporation method. Chapter II: Formulation and evaluation of oxybutynin chloride nanosponge by emulsion solvent diffusion/salting out method. Part II: Formulation and evaluation of oxybutynin chloride nanosponge compressed tablets. Chapter I: Formulation and evaluation of oxybutynin chloride nanosponge compressed tablets. Chapter II: Stability study of oxybutynin chloride nanosponge compressed tablets. Part III: Bioequivalence of oxybutynin chloride compressed tablets | ||
530 | _aIssued also as CD | ||
653 | 4 | _aCertain drug | |
653 | 4 | _aNanoparticles | |
653 | 4 | _aOral drug delivery system | |
700 | 0 |
_aFathy Ibrahim Abdallah , _eSupervisor |
|
700 | 0 |
_aMagdy Ibrahim Mohamed , _eSupervisor |
|
700 | 0 |
_aMohamed Aly Kassem , _eSupervisor |
|
905 |
_aNazla _eRevisor |
||
905 |
_aShimaa _eCataloger |
||
942 |
_2ddc _cTH |
||
999 |
_c79218 _d79218 |