000 03104cam a2200325 a 4500
003 EG-GiCUC
008 200924s2020 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2020.En.A
100 0 _aEngy Atef Boshra
245 1 0 _aAssessment of serum citrulline level and its correlation to nutritional status and adherence to gluten free diet in a cohort of Egyptian Celiac Disease Patients /
_cEngy Atef Boshra ; Supervised Ayman Emil Eskander , Shrouk Moataz Sayed , Radwa Marawan Abdelhalim
246 1 5 _aقياس نسبة السترولين بالدم لمجموعة من المرضى المصريين المصابين بمرض السيلياك وعلاقتها بالحالة الغذائية للمرضى و تاثير الطعام الخالى من الغلوتين
260 _aCairo :
_bEngy Atef Boshra ,
_c2020
300 _a170 P. :
_bcharts , facsmilies ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aBackground and aim: Celiac disease (CD) is a chronic inflammatory bowel condition triggered by gluten ingestion. It characterized predominately by intestinal symptoms that lead to malabsorption syndrome and stunted growth in young children. The only significant treatment is lifelong gluten free diet (GFD). The aim of the study is assessment of prevalence of malnutrition among CD patients and testing citrulline level and its correlation to nutritional status and adherence to gluten free diet in a cohort of Egyptian CD patients Methods: This is a case control cross sectional study was conducted at Pediatric Gastroenterology unit, Cairo University Pediatric Hospital. Sixty patients with CD with or without history of gluten free diet less than 6 months duration and other sixty children age- and sex-matched controls were enrolled. Clinical and laboratory data were compared between the two groups. Serum citrulline level was analyzed in all patients. Results: Our study revealed that the results of weight z-score, height z-score, TSF and MUAC were shown significant lower values in case group in comparison to control groups. According to GOMEZ classification, protein energy malnutrition represented 53.3% (64/120) of all the studied children. The frequency was highly significant among CD patients. CD patients showed a significantly lower citrulline levels with a mean (SD) 785.50 ± 381.33 pg/ml, compared to higher levels in healthy controls (mean 1831.81 ± 897.99pg/ml).
530 _aIssued also as CD
653 4 _aCeliac disease
653 4 _aMalabsorption syndrome
653 4 _aShort stature
700 0 _aAyman Emil Eskander ,
_eSupervisor
700 0 _aRadwa Marawan Abdelhalim ,
_eSupervisor
700 0 _aShrouk Moataz Sayed ,
_eSupervisor
905 _aAmira
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c79650
_d79650