000			03300cam a2200349 a 4500
003			EG-GiCUC
005			20250223032658.0
008			210124s2020 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.18.M.Sc.2020.Re.I
100	0		_aReham Abdelhameed Mohamed Ali Elemam
245	1	0	_aIncidence of diabetic nephropathy in early type 2 diabetic Egyptian patients / _cReham Abdelhameed Mohamed Ali Elemam ; Supervised Hoda Abdelsatar Elrawy , Laila Ahmed Rashed , Sameh Abdallah Eldewe
246	1	5	_aمعدل حدوث اعتلال الكلى السكرى فى المرضى المصريين حديثى الاصابة بمرض السكر النوع الثانى
260			_aCairo : _bReham Abdelhameed Mohamed Ali Elemam , _c2020
300			_a64 P. : _bcharts , facimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
520			_aBackground: diabetic nephropathy (DN) is the chronic loss of kidney function occurring in those with diabetes mellitus. The estimated glomerular filtration rate (eGFR) may progressively fall from a normal to a point at which the patient is said to have end-stage kidney disease (ESKD). It usually is slowly progressive over years. The status of DN may be monitored by measuring two values: the amount of protein in the urine - proteinuria; and a blood test called the serum creatinine.There are also new biomarkers for detection of proteinuria in diabietic nephropathy as Neutrophil Gelatinase Associated lipocalin (NGAL) NGAL is a new early biomarker for renal injury that precedes proteinuria (NGAL) appears to be one of the most frequently investigated and most promising biomarkers for the early diagnosis of kidney injury. Aim of the work: detection of diabetic nephropathy by albumin creatinineratio and detection of neutrophil gelatinase associated lipocalin level in serum in early type 2 diabetic egyptian patients.Patients and methods : This study was conducted on 60 patients with type 2 diabetes mellitus with 5 years duration of diabetes and 36 controls(non diabetic). All of them subjected to thorough history taking , clinical examination and the following Laboratory tests: Fasting blood glucose , 2h post prandial blood glucose , HbA1C , lipid profile ,fundus examination , urinary albumin/creatinine ratio and NGAL level in serum.Results :prevelance of diabetic nephropathy was 85% of patients(based on urinary albumin /creatinine ratio ), significant positive correlation of serum NGAL with diabetic nephropathy and significant positive correlation of serum NGAL with Hba1c. Conclusion :incidence of diabetic nephropathy is high in first 5 years of diagnosis of diabetes and Serum NGAL level can detect diabetic nephropathy
530			_aIssued also as CD
653		4	_aDiabetes Mellitus
653		4	_aDiabetic nephropathy
653		4	_aNephropathy biomarkers and NGAL.
700	0		_aHoda Abdelsatar Elrawy , _eSupervisor
700	0		_aLaila Ahmed Rashed , _eSupervisor
700	0		_aSameh Abdallah Eldewe , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c79686 _d79686