| 000 | 02578cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032707.0 | ||
| 008 | 210221s2020 ua d f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.11.28.M.Sc.2020.Sh.A | ||
| 100 | 0 | _aSherif Ashraf Moneer | |
| 245 | 1 | 0 |
_aAssessment of oxidative stress status in critically ILL pediatric patients / _cSherif Ashraf Moneer; Supervised Gehan Hussien Ahmed , Hanaa Reyad Abdallah , Miriam Magdy Aziz |
| 246 | 1 | 5 | _aتقييم حالة الاجواد التأكسدى فى الأطفال ذوى الحالات المرضية الحرجة |
| 260 |
_aCairo : _bSherif Ashraf Moneer , _c2020 |
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| 300 |
_a129 P. : _bcharts ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics | ||
| 520 | _aBackground: An excessive production of free radicals contributes to an increased burden of oxidative stress that may be implicated in the pathophysiology of tissue injury of various organs and in systemic dysfunction in critically ill patients. Objectives: To evaluate oxidants and antioxidants levels in critically ill pediatric patients. Patients and Methods: The study included 50 pediatric patients; 25 critically ill and 25 control. All patients were subjected to detailed medical history, thorough clinical examination. The degree of critical illness was assessed according to qSOFA score. Laboratory investigations included complete blood count, malondialdehyde (MDA) as an index of lipid peroxiadation, total antioxidant capacity (TAC) and paraoxonase-1as an index of antioxidants level. Results: there was statistically significant increase in the level of Serum MDA and TAC in ICU patients than control with p-value < 0.001 and < 0.001 respectively, and decrease in serum paraoxonase-1in cases than control with p-value < 0.001. TAC was significant increased in patients with septic shock p-value = 0.042. Positive significant correlation between MDA and AST (p-value= 0.015,r= 0.481), TAC and AST (p-value= 0.005, r= 0.542) and TAC and INR (p-value= 0.042, r= 0.409) | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aCritical illness | |
| 653 | 4 | _aOxidative stress | |
| 653 | 4 | _aSepsis | |
| 700 | 0 |
_aGehan Hussien Ahmed , _eSupervisor |
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| 700 | 0 |
_aHanaa Reyad Abdallah , _eSupervisor |
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| 700 | 0 |
_aMiriam Magdy Aziz , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aNazla _eRevisor |
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| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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_c79973 _d79973 |
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