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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.16.03.M.Sc.2020.Sa.H
100 0 _aSara Mohamed Mohamed Abdallah
245 1 0 _aHypoglycemic effect of Ginger and Husk Tomato on alloxan-induced diabetic rats in Egypt and Nigeria /
_cSara Mohamed Mohamed Abdallah ; Supervised Amira Shawky Soliman , Ghada Zaghloul Abbass , Mohamed Said Abbas
246 1 5 _aتأثير الزنجبيل والحرنكش على انخفاض مستوى سكر الدم فى الفئران المصابة بالداء السكرى فى مصر ونيجيرى
260 _aCairo :
_bSara Mohamed Mohamed Abdallah ,
_c2020
300 _a144 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of African Postgraduate Studies - Department of Natural Resources
520 _aDiabetes mellitus and associated complications continue to be a major health concern. The estimated number of diabetic patients is increasing worldwide despite new medicine discoveries. It is likely to increase to over 300 million by the year 2025. According to IDF diabetes Atlas 2015, an adult with diabetes in Egypt reaches 8.1 million. Due to the side effects of synthetic anti-diabetic drugs, the search for safe and effective anti-diabetic agents continues to be an important area of research. Physalis peruviana Linn. (Family Solanaceae) commonly called 2Harankash3 in Egypt is a small tropical annual herb. It is used in ethno medicine for treating malaria, asthma and hepatitis. Zingiber officinale(family Zingiberaceae)commonly called "Zangabil" in Egypt is a 2 - 4 foot tall perennial, underground plant with narrow, bright green, grass-like leaves.It is reported to exert anti-microbial, anti-nausea, anti-pyretic analgesic, anti-inflammatory, hypoglycemic anti-ulcer, antiemetic, cardio tonic, anti-hypertensive, hypolipidemic, anti-platelet aggregation effects.We aimed to investigate possible anti-diabetic, hypo-lipidaemic and antioxidant effects of Physalis peruviana and Zingiber officinaleon experimentally alloxan-induced diabetes mellitus. Forty-nine rats were divided into 7 groups [(7 rats/group]: Normal &6 diabetics groups with different treatments; treatments: Non, Glibenclamide, dried Physalis, dried Zingiber, hysalis p. ethanolic extract, Zingiberaqueous extract). The experiment lasted for 6 weeks. Fasting blood serum was analyzedfor blood glucose, cholesterol, HDL-C, LDL-C and triacylglycerol levels. Also HbA1c and MDA were analyzed. Dried Physalis powder or its ethanolic extract and dried ginger or its extract groups of rats were significantly effective in lowering serum glucose, cholesterol and triacylglycerol, also increase HDL-C levels compared with the control diabetic rats which exhibit hyperglycaemia accompanied with weight loss. The present results indicate that dried Physalis powder or its ethanolic extract and dried ginger or its extract possesses hypoglycemia, hypocholesterolemic and hypolipidemic potential
530 _aIssued also as CD
653 4 _aAntidiabetic drugs
653 4 _aPhysalis peruviana L
653 4 _aZingiber officinale
700 0 _aAmira Shawky Soliman ,
_eSupervisor
700 0 _aGhada Zaghloul Abbass ,
_eSupervisor
700 0 _aMohamed Said Abbas ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c80260
_d80260