000 025120000a22003370004500
003 EG-GICUC
005 20250223032722.0
008 061014s2005 ua a f m 000 0 eng d
040 _aEG-GICUC
_beng
_cEG-GICUC
041 0 _aEng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.14.M.Sc.2005.Mo.L.
100 0 _aMohamed Mahmoud Abdelslam Abdalla
245 1 0 _aLiver protection during major liver resection /
_cMohamed Mahmoud Abdelslam Abdalla ; Supervised Abdalkader Abdelfattah Kotb , Hussein Mahmoud Khairy , Toumas Van gulik
246 1 5 _aوقاية الكبد اثناء عمليات الاستئصال الجزئى للكبد
260 _aCairo :
_bMohamed Mahmoud Abdelslam Abdalla ,
_c2005
300 _a144P :
_bill. ;
_c30cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of General Surgery
520 _aThe effects of liver I / R injury are still a major concern during extensive liver resections in which clamping of the afferent vessels are necessary to minimize blood loss Although extensive research has been conducted over the past decades to explore the mechanisms involved in I / R injury , these complex mechanisms , involving several pathways , are not yet fully understood Animal studies are still an important part of current research , especially when mechanistic issues are investigatedThe decrease in intra - operative and postoperative complications has improved the outcome of major liver surgery over the last decadesThe reduction of intra - operative blood loss by clamping the afferent vessels to the liver , with or without clamping of the supra - hepatic and infra - hepatic caval vein , significantly contributed to this achievement A further decrease in postoperative morbidity can be accomplished by reducing procedure related liver injury , such as I / R injuryThe objective of this study was to decrease liver I / R injury by means of a decrease in core liver temperature of 10?C or 18?C , achieved by in situ hypothermic perfusion of the liver during ischemia using three types of different perfusion solutions
530 _aIssued also as CD
653 4 _aLiver protection
653 4 _amajor liver resection
700 0 _aAbdalkader Abdelfattah Kotb ,
_eSupervisor
700 0 _aHussein Mahmoud Khairy ,
_eSupervisor
700 0 _aToumas Van gulik ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAmira
_eCataloger
905 _aMustafa
_eRevisor
942 _2ddc
_cTH
999 _c80444
_d80444