000 02851cam a2200349 a 4500
003 EG-GiCUC
005 20250223032722.0
008 210329s2020 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.15.Ph.D.2020.Ah.S
100 0 _aAhmed Othman Ahmed Sayed Ahmed
245 1 0 _aStudy effects of adding cabergoline by different doses to coasting reduce the incidence ovarian hyperstimulation syndrome :
_bA randomized controlled study /
_cAhmed Othman Ahmed Sayed Ahmed ; Supervised Tarek Fawzy , Ahmed Maged , Abdelghany Mohamed
246 1 5 _aدراسة آثار إضافة كابر جولين بجرعات مختلفة إلى إيقاف المنشط فى تحفيظ نسبة متلازمة فرط الأستجابة للمبيض :
_bدراسة عشوائية منضبطة
260 _aCairo :
_bAhmed Othman Ahmed Sayed Ahmed ,
_c2020
300 _a126 P. :
_bcharts ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics
520 _aBackground:Ovarian hyperstimulation syndrome (OHSS) is a potentially severe iatrogenic complication of controlled ovarian stimulation. Combining coasting and cabergoline may be beneficial for preventing OHSS, but this has not been well investigated. Objectives:To compare the effectiveness and safety of combined cabergoline and coasting versus coasting alone for preventing OHSS in high-risk women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). Methods:The present double-blinded randomized controlled trial was conducted at Al-Ahram Fertility Center (Mansoura, Egypt) between January 2016 and December 2018. 200 patients undergoing IVF/ICSI at high risk of OHSS were equally randomized to coasting or combined coasting and cabergoline. The main measured outcomes were the rate and severity of OHSS, number of retrieved oocytes, number and quality of embryos, as well as rates of fertilization, implantation,chemical, and clinical pregnancy. Results:The combination group has a lower rate of OHSS (4% vs. 18%, p 0.001) and higher number of good embryos (12.1 ±3.93 vs. 6.9 ±2.67; p< 0.00). There were no significant differences between the two groups in the number of retrieved oocytes as well as the rates of fertilization, implantation,chemical, and clinical pregnancy
530 _aIssued also as CD
653 4 _aCabergoline
653 4 _aHyperstimulation syndrome
653 4 _aOvarian hyperstimulation syndrome (OHSS)
700 0 _aAbdelghany Mohamed ,
_eSupervisor
700 0 _aAhmed Maged ,
_eSupervisor
700 0 _aTarek Fawzy ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c80453
_d80453