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003 | EG-GiCUC | ||
005 | 20250223032736.0 | ||
008 | 210517s2019 ua d f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aM.Sc | ||
099 | _aCai01.24.05.M.Sc.2019.Ji.P | ||
100 | 0 | _aJilan Saber Rizk Ibrahim | |
245 | 1 | 0 |
_aPolypyrrole-Gold nanocomposites as a photothermal agent for murine cancer treatment / _cJilan Saber Rizk Ibrahim ; Supervised Tarek Abdallah Etayeb , Neamat Hanafi Ahmed , Mahmoud Ashour Sliem |
246 | 1 | 5 | _aمتراكبات النانو من البوليبيرول- الذهب كعامل ضوئى حرارى لعلاج سرطان الفئران |
260 |
_aCairo : _bJilan Saber Rizk Ibrahim , _c2019 |
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300 |
_a101 P. : _bcharts ; _c25cm |
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502 | _aThesis (M.Sc.) - Cairo University - National Institute of Laser Enhanced Sciences (NILES) - Department of Laser Application Environmental Metrology, Photochemistry photobiology and Agriculture | ||
520 | _aPhotothermal nanoplatforms with good biocompatibility are greatly desired in the exploration of novel therapeutic methodologies. The surface coating of gold nanorods (Au NRs) by polypyrrole nanoparticles (PPy NPs) can be used not only in increasing the biocompatibility of Au NRs for treatment, but also in enhancing their photothermal efficiency. Polypyrrole-gold nanocomposites (PPy-Au NCs) were synthesized using ex-situ polymerization method of the modified pyrrole monomer. This work demonstrated the synthesis of PPy-Au NCs and their photothermal effect, in comparison to Au NRs and PPy NPs. Additionally, histological analysis was performed to investigate the efficiency of PPy-Au NCs in reducing tumor progression and ablating Ehrlich carcinoma (EC) bearing mice using polychromatic, polarized and low energy (PPLE) light source. PPLE light sources could provide a safer and more practical approach to photothermal therapy (PTT).Therefore, we propose that PTT based on PPy-Au NCs as a photothermal agent and the polychromatic, polarized and low energy light as a power source can serve as a new effective treatment for cancer tumors. This work will be useful for designing enhanced photothermal properties and further applications in nanomedicine | ||
530 | _aIssued also as CD | ||
653 | 4 | _aMurine cancer treatment | |
653 | 4 | _aPhotothermal agent | |
653 | 4 | _aPolypyrrole-Gold nanocomposites | |
700 | 0 |
_aMahmoud Ashour Sliem , _eSupervisor |
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700 | 0 |
_aNeamat Hanafi Ahmed , _eSupervisor |
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700 | 0 |
_aTarek Abdallah Etayeb , _eSupervisor |
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856 | _uhttp://172.23.153.220/th.pdf | ||
905 |
_aNazla _eRevisor |
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905 |
_aShimaa _eCataloger |
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942 |
_2ddc _cTH |
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_c80912 _d80912 |