000			03183cam a2200325 a 4500
003			EG-GiCUC
008			210529s2021 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.10.09.Ph.D.2021.Am.A
100	0		_aAmany Dieb Bahr Dieb
245	1	0	_aAdvanced studies on pasteurellosis in farm animals / _cAmany Dieb Bahr Dieb ; Supervised Mahmoud Mohamed Amin Abdalhady , Fayez Awad Allah Salib , Yousef Adel Soliman
246	1	5	_aدراسات متقدمة عن عدوى الباستريلا فى حيوانات المزرعة
260			_aCairo : _bAmany Dieb Bahr Dieb , _c2021
300			_a122 P. : _bcharts ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Internal Medicine and Infectious Desiases
520			_aPasteurella multocida(P. multocida) and Mannheimia haemolytica (M. haemolytica) are widespread pathogens, resulting in economically significant animal diseases. This study aimed to investigate some of the epidemiological aspects of P. multocidaand M. haemolyticainfections in Egypt, proper diagnosis of P. multocidaand M. haemolyticainfections, describe the distribution of capsular types of P. multocidaisolates, measure the prevalence of multi-drug resistance in bacterial isolates recovered from cattle, buffaloes, sheep, and goats (ruminants) suffering from respiratory manifestations,investigate the humoral immune responses and protective immunity conferred by a preparedpolyvalent formalin-killedP. multocidaand M. haemolyticavaccine with the use ofMontanideTMISA 71 VG oil as an adjuvant in mice along with a biochemical and immunological evaluation of the prepared vaccine in sheep. A total of 155 deep nasal swabs were collected from 20 cattle, 37 buffaloes, 80 sheep, and 18 goats. Detection of 24 P. multocidaand 12 M. haemolyticaisolates from tested samples was carried out by bacteriological isolation, then identified by biochemical tests, and confirmed by polymerase chain reaction (PCR). The highest rate of infection with P. multocidaand M. haemolyticahas been found in young males (0-6 months age group). P. multocidacapsular group A was found in the majority of the P. multocidastrains (87.5%), while group D bacteria were identified in only three samples. Capsular groups B, E, and F have not been detected. The antimicrobial susceptibility pattern of P. multocidaand M. haemolyticaisolates indicated a high prevalence of multi-resistance to the majority of antimicrobials used as high resistance was detected against ampicillin, amoxicillin, penicillin-G, tetracycline, streptomycin, cefotaxime, and chloramphenicol, however, 100% sensitivity was demonstrated by M. haemolyticaisolates to gentamicin
530			_aIssued also as CD
653		4	_aAntimicrobial resistance
653		4	_aBiochemical
653		4	_aCapsular groups
700	0		_aFayez Awad Allah Salib , _eSupervisor
700	0		_aMahmoud Mohamed Amin Abdalhady , _eSupervisor
700	0		_aYousef Adel Soliman , _eSupervisor
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c81068 _d81068