000			03452cam a2200325 a 4500
003			EG-GiCUC
008			210605s2021 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.11.01.Ph.D.2021.Ha.R
100	0		_aHala Ahmed Elsabbagh
245	1	0	_aRandomized comparative trial of pre-surgical lumbar epidural analgesia with bilateral erector spinae block for perioperative pain management in lumbar spine surger / _cHala Ahmed Elsabbagh ; Supervised Shereen Mostafa Amin , Hebatallah Salah Abdelhamid , Amr Kamal Abdelmohsen
246	1	5	_aدراسة عشوائية لمقارنة تسكين فوق الام الجافية بتسكين عضلة ناصبة الفقرات على الجانبين قبل الجراحة لعلاج الألم المصحوب بجراحة العمود الفقرى القطنى
260			_aCairo : _bHala Ahmed Elsabbagh , _c2021
300			_a63 P. : _bcharts , fascimiles ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anaesthesia
520			_aBackground: Spine surgery is one of the most painful surgical procedures, with median pain scores (using the 0-10 NRS-numeric rating scale) on the first postoperative day ranging from 5 (spinal decompression) to 7 (spinal fusion).The epidural analgesia is a well-established and highly effective block where the local anaesthetics (LA) spread from the epidural space to the spinal cord, nerve roots, and cerebrospinal fluid. However, the Erector Spinae plane block (ESPB) proved to be efficient in controlling post-operative pain in a variety of surgeries including the spine surgery. Our aim was to compare the first demand to rescue analgesia postoperatively in epidural and ESPB groups. Secondary outcomes were to compare NRS pain score, postoperative morphine consumption, changes in arterial blood pressure (ABP), heart rate (HR) and adverse events. Patients and Methods: Sixty patients scheduled for elective lumbosacral spine decompression and fixation surgery were enrolled in the study. Patients were allocated into 2 groups, 30 patients each. In the epidural Group, patients underwent ultrasound-guided single-shot epidural injection, while in the ESPB group, patients were handled with ultrasound-guided single-shot ESPB.Results: time to first demand of rescue analgesia in the ESPB group (11.5 hours) was longer than that in the epidural group (7 hours). Moreover, the ESPB group decreased the 24hour consumption of morphine (3.5mg) when compared with the epidural group (7.5mg).The NRS pain score decreased post-operatively in both groups when compared to the baseline throughout all assessment points. Between both groups, the NRS was lower in the epidural group immediately postoperative and at 1, 2 and 8 hours. However, at 4, 12 and 24 hours, both groups were comparable.The study also showed that the number of patient who experienced hypotension and tachycardia intra-operatively was more in the epidural group than the ESPB group
530			_aIssued also as CD
653		4	_aErector Spinae plane Block
653		4	_aPain
653		4	_aSpine Surgery
700	0		_aAmr Kamal Abdelmohsen , _eSupervisor
700	0		_aHebatallah Salah Abdelhamid , _eSupervisor
700	0		_aShereen Mostafa Amin , _eSupervisor
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c81163 _d81163