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008 210614s2020 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.09.08.M.Sc.2020.Ah.A
100 0 _aAhmed Alaa Eldin Mahmoud Gamal Eldin Fouad
245 1 0 _aAssessment of wound healing in irradiated albino rat after the use of bone marrow-derived mesenchymal stem cells and nano-scaffold :
_bAn experimental in vivo study /
_cAhmed Alaa Eldin M. Gamal Eldin Fouad ; Supervised Azza Ezz Elarab , Soheir Saad Korraa , Marwa Mostafa A Fattah A Khalek
246 1 5 _aتقييم التئام الجروح فى الجرذان البيضاء المشععة بعد استخدام الخلايا الجذعية الميزنشيمية المستخرجة من نخاع العظام و سقالة النانو :
_bدراسة تجريبية في الجسم الحى
260 _aCairo :
_bbAhmed Alaa Eldin Mahmoud Gamal Eldin Fouad ,
_c2020
300 _a134 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine- Department of Periodontology
520 _aAim of the work: was to investigate the efficacy of bone marrow mesenchymal stem cells (BM-MSCs) combined with nanoscaffold in enhancing wound healing in irradiated albino rats Methodology: Sixty-four male rats ranging from 140 to150 g were used in this study divided into four equal groups. All rats were subjected to 6 Gray gamma irradiation. Three days post-irradiation, a circular incision was performed having a diameter of 1.5 cm on the back of the rats. The Control group didn{u2019}t receive any treatment, the Nano-scaffold group (NS), Mesenchymal stem cells group (MSC), and Combination group (MSC + NS).The nanoscaffold was put on the surgical wound in (NS and MSC+NS group) and stem cells injected in (MSC and MSC+NS group), and further divided into two subgroups according to the date of the sacrifice on 7 and 14 days and the excised wound was examined. Results: Clinically, the least anteroposterior and lateral length of the wound was recorded in the combination group (MSC + NS). Antero-posterior length significantly decreased by time however the percentage of decrease was the least as compared to the other groups. Histologically, the wound site was completely covered with intact epithelium and thin keratin layer in all treatment groups.The underlying dermis showed normal collagen fibers which were dense and well arranged with the presence of many hair follicles and sebaceous glands
530 _aIssued also as CD
653 4 _aAssessment of wound healing
653 4 _aBone marrow mesenchymal stem cells (BM-MSCs)
653 4 _aNano-scaffold
700 0 _aAzza Ezz Elarab ,
_eSupervisor
700 0 _aSoheir Saad Korraa ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c81295
_d81295