000 02500cam a2200337 a 4500
003 EG-GiCUC
005 20250223032753.0
008 210629s2018 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.09.04.M.Sc.2018.Am.I
100 0 _aAmal Mostafa Sayed Mostafa
245 1 0 _aImmunohistochemical expression of cyclooxgynase-2 and transforming growth factor-Ý1 in adenoid cystic carcinoma of salivary gland :
_bIn vitro study /
_cAmal Mostafa Sayed Mostafa ; Supervised Amal Hassan Abdelrahman , Reham Salah Hamed
246 1 5 _aالتوزيع المناعى الهيستوكيميائى للسيكلو-اوكسيجينيز- 2و معامل النمو الانتقالى بيتا- 1 فى السرطان الشبه غدى التكيسى للغدد اللعابية:
_bدراسه في المختبر
260 _aCairo :
_bAmal Mostafa Sayed Mostafa ,
_c2018
300 _a107 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Pathology
520 _aThe aim of the present study was to investigate the immunohistochemical expression of TGF-Ý1 and COX-2 in different variants of ACC (cribriform, tubular/trabecular and solid) and also correlate the expression of the two markers with each other. A total of 30 specimens were collected. The standard avidin-biotinperoxidase technique has been used in the present study for detection of TGF- Ý1and COX-2, the immunostaining of these markers were evaluated by an image analyzer computer system. The study demonstrated that COX-2 and TGF-Ý1expression was significantly increased in solid variant of ACC than other patterns and thus concluded that COX-2 and TGF-Ý1expression are directly related to ACC histopathological grade. The study also showed a significant direct correlation between the immunostaining of TGF-Ý1 and COX-2.In most of cases the increase in COX-2 expression is associated with increase in TGF-Ý1expression, which may indicate that TGF-Ý1 induce the expression of COX-2
530 _aIssued also as CD
653 4 _aCyclooxgynase-2
653 4 _aFactor-Ý1
653 4 _aSalivary gland
700 0 _aAmal Hassan Abdelrahman ,
_eSupervisor
700 0 _aReham Salah Hamed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c81419
_d81419