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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.26.M.Sc.2021.No.A
100 0 _aNourhan Atef Sayed
245 1 0 _aAssessment of the effect of extracts of Calotropis procera leaves on experimental Hymenolepis nana infection /
_cNourhan Atef Sayed ; Supervised Ahmed Hemmat Eassa , Mona Mostafa Khater, Shaimaa Helmy Elsayed
246 1 5 _aتقييم تأثير المستخلصات من أوراق نبات العشار على العدوى التجريبيه للهيمينوليبس نانا
260 _aCairo :
_bNourhan Atef Sayed ,
_c2021
300 _a138 P . :
_bcharts , facsmilies ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Parasitology
520 _aHymenolepis nana is the commenst cestodal infection worldwide. Infection prevalence rate increases in tropical areas especially among children. This study was conducted to assess the anticestodal effect of Calotropis procera crude aqueous extract, crude methanolic extract and combined treatment of these two extracts with PZQ on H. nana worms in mice. Different parasitological parameters and tegumental studies were done on the adult worms. Also, hitopathological studies were done on the larval stage (cysticercoids). The total number of mice was divided into two groups. The first group received treatment and was sacrificed on the 4th day post infection to assess the cysticercoid stage. The other group received treatment after the development of the adult stage, confirmed by detection of eggs in stool samples Both PZQ and C. procera extracts and their combinations showed anthelminthic effects on H. nana worms; resulting in significant reduction of warm burden, total egg output and viable egg count. Adult worms showed clear tegumental changes and abnormalities with both treatments and their combinations. However, praziquantel was more rapid in action. Also, both treatments and their combinations resulted in significant reduction in cysticercoid stage count with evident histopathological changes. Therefore, C. procera leaves have anticestodal effects against H. nana with promising expectations to be an alternative plant based anthelminthic
530 _aIssued also as CD
653 4 _aC. procera leaves
653 4 _aHymenolepis nana
653 4 _aPraziquantel
700 0 _aAhmed Hemmat Eassa ,
_eSupervising
700 0 _aMona Mostafa Khater,
_eSupervising
700 0 _aShaimaa Helmy Elsayed ,
_eSupervising
856 _uhttp://172.23.153.220/th.pdf
905 _aAmira
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c81436
_d81436