000 02888cam a2200349 a 4500
003 EG-GiCUC
005 20250223032757.0
008 210731s2020 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.07.M.Sc.2020.Ne.F
100 0 _aNehal Diaa Abdelhameed
245 1 0 _aFrequency of HBV infection in multi-transfused vaccinated patients with hematological disorders /
_cNehal Diaa Abdelhameed ; Supervised Azza Ahmed Aboulenein , Ilham Youssry Ibrahim , Nermeen Ahmed Eldesoukey
246 1 5 _aفى مرضى امراض الدم اللذين سبق تطعيمهم و تعدد نقلهم للدم HBV قياس تكرار العدوى
260 _aCairo :
_bNehal Diaa Abdelhameed ,
_c2020
300 _a117 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
520 _aIntroduction: Transfusion of blood and blood products is an important therapy for many patients; however, it still carries the risk of transmission of infection. Transfusion of Hepatitis B virus is common through blood transfusion .This highlights the importance of combined HBsAg and anti-HBc screening to eliminate blood-transmitted HBV. Aim of the work: The aim of this study was to screen the vaccinated multi-transfused patients in the outpatient clinic for hematologic disease at Aborish pediatric hospital, for HBV and to assess the prevalence of HBV among those patients.This way reflect the safety of the environment, medical procedures including blood transfusion and the immune status of those patients. Material and Method: The study was conducted on 805 multi-transfused patients who had been attending the outpatient pediatric hematology clinic. Plasma blood samples were collected for HBV rapid screening test and serum samples were collected for serological and molecular analysis of positive cases. Results: Our results of HBV screening using RDT revealed 3 positive cases out of 805. The first case showed HBsAg positive, HBsAb was negative (2mIU/ml), HBcAb positive, HBeAg was positive and high viral load.The second case showed showed HBsAg positive, HBsAb negative (2mIU/ml), HBcAb positive, HBeAg was negative and intermediate viral load. And the third case showed showed HBsAg negative, HBsAb was positive (20mIU/ml), HBcAb positive, HBeAg was negative with undetectable titer
530 _aIssued also as CD
653 4 _aChemiluminescence
653 4 _aHBV
653 4 _aPCR
700 0 _aAzza Ahmed Aboulenein ,
_eSupervisor
700 0 _aIlham Youssry Ibrahim ,
_eSupervisor
700 0 _aNermeen Ahmed Eldesoukey ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c81527
_d81527