| 000 | 02690cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032805.0 | ||
| 008 | 210823s2021 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.11.31.Ph.D.2021.Ma.H | ||
| 100 | 0 | _aMahmoud Zaki Gaafar Zaki | |
| 245 | 1 | 0 |
_aHepasphere drug eluting beads transarterial chemoembolization in treatment of hepatocellular carcinoma : _bA comparative study / _cMahmoud Zaki Gaafar Zaki ; Supervised Mohamed Mostafa Hamed , Ayman Yosry Abdelrahim , Omar Abdelaziz Ahmed Hamada |
| 246 | 1 | 5 |
_aالحقن الشريانى بكرات هيباسفير الباعثة للعلاج الكيماوى فى علاج أورام الكبد : _bدراسة مقارنة |
| 260 |
_aCairo : _bMahmoud Zaki Gaafar Zaki , _c2021 |
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| 300 |
_a173 P. : _bcharts , facimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis | ||
| 520 | _aTACE is intra-arterial injection of a chemotherapeutic drug (e.g. doxorubicin) followed by feeding artery embolization, which leads to a combination of a cytotoxic and ischemiceffect (6).The injection should be continued until vessel-stasis is achieved. TACE is a variable procedure in which different chemotherapeutic drugs, embolic agents, and treatment schedules are applied (7), leading tovariable efficacy outcomes (8). The most commonly used technique is conventional TACE (cTACE) in which a mixture of the cytotoxic drug and lipiodol is injected in the tumoral feeding arteries of HCC, then followed by the embolic agent, e.g. gelatin sponge (gelfoam). Because of the kupffer calls-lack, HCCs retain lipiodol, which will facilitate the retention of the cytotoxic compound as well. However, significant leakage of the chemotherapeutic drug into the systemic circulation has been identified after cTACE (9). In order toavoid this systemic effect, polyvinyl alcohol microparticles loaded with doxorubicinwere developed (10). The microparticlesocclude the feeding arteries while slowly emitting doxorubicin into the tumor, leading to maintained ischemia and prolonged drug effect | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aEluting beads transarterial chemoembolization | |
| 653 | 4 | _aHepasphere | |
| 653 | 4 | _aTreatment of hepatocellular carcinoma | |
| 700 | 0 |
_aAyman Yosry Abdelrahim , _eSupervisor |
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| 700 | 0 |
_aMohamed Mostafa Hamed , _eSupervisor |
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| 700 | 0 |
_aOmar Abdelaziz Ahmed Hamada , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c81824 _d81824 |
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