000			02221cam a2200349 a 4500
003			EG-GiCUC
005			20250223032821.0
008			210927s2020 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.11.28.Ph.D.2020.Ba.C
100	0		_aBayoumi Abdelaty Emam
245	1	0	_aClinical, neuroimaging and genetic study in patients with ponto-cerebellar malformations / _cBayoumi Abdelaty Emam ; Supervised Sawsan Abdelhady Hassan , Ghada Mohamed Elhossiny Abdelsalam , Marian Yousry Fahmy
246	1	5	_aدراسة اكلينيكية ودراسة الاشعة التصويرية للمخ والنتائج الوراثية لمرضى التشوهات بالجسر المخيخى
260			_aCairo : _bBayoumi Abdelaty Emam , _c2020
300			_a202 P . : _bcharts , facsmilies ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520			_aThey represents a group of rare disorders with prenatal onset and clear evidence for time dependent loss of brain parenchyma, predominantly affecting growth and survival of neurons in the cerebellar cortex,the dentate,inferior olivary and ventral pontine nuclei.The variable involvement of supratentorial structures includes ventriculomegaly,neocortical atrophy and microcephaly.Radiologically and pathologically, they are characterized by hypoplasia and /or atrophy of the cerebellum and pons (Namavar et al.,2011).Pontocerebellar Hypoplasia (PCH) has emerged as distinct entity which includes 13 subtypes (PCH 1-13) until now. They are a group of AR neurodegenerative disorders with prenatal onset.Neuroradiological findings in all subtypes are PCH and/or atrophy of ventral pons,cerebellum
530			_aIssued also as CD
653		4	_aGenetic study
653		4	_aNeuroimaging
653		4	_aPonto-Cerebellar
700	0		_aGhada Mohamed Elhossiny Abdelsalam , _eSupervising
700	0		_aMarian Yousry Fahmy, _eSupervising
700	0		_aSawsan Abdelhady Hassan , _eSupervising
856			_uhttp://172.23.153.220/th.pdf
905			_aAmira _eCataloger
905			_aNazla _eRevisor
942			_2ddc _cTH
999			_c82334 _d82334