000			03255cam a2200349 a 4500
003			EG-GiCUC
005			20250223032821.0
008			210927s2021 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.08.07.Ph.D.2021.Sh.P
100	0		_aShrouq Hussein Abdullah Ali Sweilam
245	1	2	_aA phytochemical and biological study of echinops erinaceus Kit Tan : _bFamily asteraceae / _cShrouq Hussein Abdullah Ali Sweilam ; Supervised Essam Abdelhamid Abdelsattar , Moshera Mohamed Elsherei , Omayma Dawood Elgindi
246	1	5	_aدراسة فيتوكيميائية وبيولوجية لنبات اشنوبس اريناسيس كيت تان : _bالعائلة النجمية
260			_aCairo : _bShrouq Hussein Abdullah Ali Sweilam , _c2021
300			_a239 P . : _bcharts ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy
520			_aThe Asteraceae family occupies the highest position in the plant kingdom, it consists of 1400 genera and 25000 species, is classified into 3 subfamilies and 17 tribes, 222 species of Asteraceae family are distributed in Saudi Arabia, and 120 species of Echinops genus are found in different regions such as north and tropical Africa, Europe, Central Asia and Mediterranean region. The classification of Echinops genus is based on morphological characteristics but taxonomically is still unclear. Echinops species have been reported to contain several biologically active compounds. Therefore, this species can be exploited for the treatment of many diseases as antioxidant, anti-inflammatory, antiulcer, anti-cancer, and antidiabetic. Echinops erinaceus Kit Tan is indigenous to Saudi Arabia and there is no previous chemical or biological reports on it. In this study, the air-dried flowering aerial parts of E. erinaceus were extracted and fractionated to give various extracts (total methanol, n-hexane, chloroform, ethyl acetate, and remaining aqueous extracts) which were estimated for their total phenolic, flavonoid, and tannin contents. On the other hand, the isolation and identification of pure compounds from the CHCl3 extract were studied. The investigation of the CHCl3 extract of E. erinaceus led to the isolation and identification of 14 compounds using different chromatographic techniques of which, four compounds designated as (erinaceosin, erinaceolic acid, erinaceol, and erinaceoside) were isolated for the first time from nature, with one rare compound (naringenin-7-O-Ý-D-(4``- trans-p-coumaroyl), along with nine known compounds (methyl oleate, ethyl oleate, taraxasterol acetate, taraxasterol, apigenin, loliolide, trans-p-coumaric acid, stigmasterol glycoside, and 5, 7, 3`, 5`, tetrahydroxy flavanone)
530			_aIssued also as CD
653		4	_aAntioxidant
653		4	_aCyclooxygenase
653		4	_aEchinops erinaceus
700	0		_aEssam Abdelhamid Abdelsattar , _eSupervising
700	0		_aMoshera Mohamed Elsherei , _eSupervising
700	0		_aOmayma Dawood Elgindi , _eSupervising
856			_uhttp://172.23.153.220/th.pdf
905			_aAmira _eCataloger
905			_aNazla _eRevisor
942			_2ddc _cTH
999			_c82337 _d82337