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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.28.Ph.D.2021.As.P
100 0 _aAsmaa Hassan Taha Hassan
245 1 0 _aPrevalence of hepatic dysfunction in pediatric patients with fontan circulation /
_c Asmaa Hassan Taha Hassan ; Supervised Amal Mahmoud Elsisi , Hanaa Mostafa Elkaraksy , Maha Fathy Sheba
246 1 5 _aمعدل انتشار الخلل فى وظائف الكبدعند مرضى اطفال الفونتان
260 _aCairo :
_bAsmaa Hassan Taha Hassan ,
_c2021
300 _a160 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aFontan is the definitive palliative operation for patients with a single ventricle (SV). Specific postoperative complications have been recognized with the increasing survival of these patients. Hepatic dysfunction is a well-known complication and is frequently referred to as Fontan associated liver disease (FALD). Fontan circulation is not regularly assessed in pediatric patients for the development of liver disease. Aim of the work: The aim of this study was to assess hepatic dysfunction in pediatric patients with Fontan circulation. Patients and methods: The study was an observational analytical study conducted on 30 patients who underwent Fontan operation more than two years before inclusion in the study and who are followed up at the Pediatric Cardiology Unit, Cairo University Children{u2019}s Hospital. All patients subjected to echocardiography, laboratory investigations, abdominal ultrasound and liver elastography. Results: The median patient age was 13 years (IQR 10{u2013}16.32), and the median duration of the Fontan operation was 5 years (IQR 3.83{u2013}9). Global longitudinal strain (GLS) was lower in 26 (86.7%), and the SV ejection fraction was reduced in 23 (76.7%), however, no correlation was found with time interval since Fontan. Þ glutamyl transferase (GGT) was elevated in 28 (93.33%), which was significantly higher in unfavorable outcome
530 _aIssued also as CD
653 4 _aFontan associated liver disease
653 4 _aFontan operation
653 4 _aSingle ventricle
700 0 _aAmal Mahmoud Elsisi ,
_eSupervisor
700 0 _aHanaa Mostafa Elkaraksy ,
_eSupervisor
700 0 _aMaha Fathy Sheba ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c82634
_d82634