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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2021.Ay.E
100 0 _aAya Magdy Khalil Shabaan
245 1 0 _aEffect of phototherapy on liver and kidney functions in treatment of neonatal hyperbilirubinemia /
_cAya Magdy Khalil Shabaan ; Supervised Heba Allah Hany Abohussein , Yosra Aboelaaga Fahmy , Balsam Sherif Fahmy
246 1 5 _aتأثير العلاج الضوئى على وظائف الكبد والكلى لدى الاطفال المصابين بفرط فى بيليروبين الدم
260 _aCairo :
_bAya Magdy Khalil Shabaan ,
_c2021
300 _a90 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aIntroduction: Neonatal jaundice is a frequent problem affecting the newborn with various etiologies. Although phototherapy is considered the standard treatment for neonatal hyperbilirubinemia, it comes with some complications, such as erythematous rashes, diarrhea, hyperthermia and electrolyte disturbance.Aim: To assess the effect of phototherapy on liver enzymes, renal functions, and serum electrolytes in jaundiced patients before and after phototherapy. Methods: This observational cross sectional study was conducted at the phototherapy NICU, Cairo University, Abu El Rich Children{u2019}s Hospital, Faculty of Medicine, Cairo University. One hunderd neonates with unconjugated hyberbilirubinemia were enrolled into the current study during the period from March 2019 to September 2019. Each neonate was subjected to detailed history taking, clinical examination and Laboratory investigations. Jaundiced neonates were placed under phototherapy naked while covering eyes and genitalia at a distance of 45-50 cm from phototherapy unit. They were managed with continuous phototherapy in open bed. The position of the baby was changed from time to time. Results: In the present study, mean TSB significantly decreased between before (16.51 ± 2.11) and after (7.49 ± 1.23) phototherapy with p value <0.001. Mean DSB showed statistically significant decrease before and after treatment (1.05 ± 0.24 vs.0.31 ± 0.25) (p<0.001). Mean AST (29.84 ± 8.23 vs. 26.83 ± 6.95) and ALT (27.79 ± 8.51 vs. 24.60 ± 8.49) showed statistically significant difference between before and after phototherapy (p<0.001). We also observed significant differences in potassium and Calcium levels (p-value of < 0.001 in each case). After treatment there were significant decreases in mean potassium (4.48 ± 1.19 vs. 3.85 ± 0.53) and Calcium 9,08 ± 0,63 vs. 7,7 ± 0,90 p<0.001
530 _aIssued also as CD
653 4 _aKidney and liver functions
653 4 _aNeonatal hyperbilirubinemia
653 4 _aPhototherapy
700 0 _aBalsam Sherif Fahmy ,
_eSupervisor
700 0 _aHeba Allah Hany Abohussein ,
_eSupervisor
700 0 _aYosra Aboelaaga Fahmy ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c83496
_d83496