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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.10.M.Sc.2021.Sa.C
100 0 _aSahar Radman Alkubati
245 1 0 _aComparative study among CO2 laser, intralesional vitamin D3 and combined intralesional vitamin D3 and CO2 laser in treatment of palmoplantar warts /
_cSahar Radman Alkubati ; Supervised Hanan Rabea Nada , Dina Ahmed Elsharkawy
246 1 5 _aدراسة مقارنة بين ليزر ثانى أكسيد الكربون :حقن فيتامين د داخل الآفة :وليزر ثانى أكسيد الكربون مع حقن فيتامين د داخل الآفة فى علاج الثآليل الراحية و الأخمصية
260 _aCairo :
_bSahar Radman Alkubati ,
_c2021
300 _a69 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology
520 _aBackground: Many therapeutic modalities are employed either alone or in combination for the treatment of palmoplantar warts.These treatment modalities are either destructive such as chemical cautery, electrocautery, cryocautery, surgical removal, and laser ablation; or immunotherapeutic modalities, which activate the immune system against the virus and suppress its activity such as intralesional candida antigen or vitamin D3 injection. Aim of work: To compare the efficacy of intralesional vitamin D injection combined with CO2 laser to the efficacy of either modality alone in the treatment of palmoplantar warts and their recurrence rate. Patients and Methods: Eighty age and sex matched patients with palmo- plantar warts who attended the outpatient Clinic of the Dermatology Department at Kasr Al-Ainy hospital were enrolled in the study. Patients were divided into 4 groups: Group A (vitamin D3 group) received intralesional injection of vitamin D3, group B (CO2 Laser group) received ablative CO2 Laser, group C (combined CO2 Laser and vitamin D3 group) received CO2 laser followed by intralesional injection vitamin D3 and group D (control group) were injected intralesionally with normal saline. Assessment was done clinically, photographically and dermoscopically before and after treatment to evaluate the response then another assessment was done after 3 months to detect any recurrence. Results: There was a statistically significant difference between the control group on one hand and the other groups on the other hand regarding the degree of response (p=0.000*). On comparing the 3 groups A, B and C, no statistically significant difference was noted regarding the degree of response, complete improvement time and incidence of recurrence. However, the incidence of side effects was significantly less in the laser only group (B) when compared to the other groups
530 _aIssued also as CD
653 4 _aCO2 laser
653 4 _aPalmoplantar warts
653 4 _aVitamin D3
700 0 _aDina Ahmed Elsharkawy ,
_eSupervisor
700 0 _aHanan Rabea Nada ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c83727
_d83727