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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.36.M.Sc.2021.Fa.R
100 0 _aFatma Alzahraa Ahmad Alsayed Ali
245 1 0 _aRespiratory and bulbar dysfunctions in amyotrophic lateral sclerosis :
_bElectrophysiologic and muscle ultrasound assessment /
_cFatma Alzahraa Ahmad Alsayed Ali ; Supervised Amani Mahmoud Nawito , Hanan Helmy Elgendy , Mye Ali Basheer
246 1 5 _aالاختلال فى وظائف التنفس والبلع فى التصلب الجانبى الضمورى :
_bتقييم باستخدام الفسيولوجيا الكهربية والموجات الصوتية للعضلات
260 _aCairo :
_bFatma Alzahraa Ahmad Alsayed Ali ,
_c2021
300 _a92 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Neurophysiology
520 _aBackground: Respiratory and bulbar dysfunctions are the leading causes of death in amyotrophic lateral sclerosis disease (ALS).The function of the diaphragm as the primary muscle of respiration can be assessed by phrenic nerve conduction studies and diaphragm ultrasound. In addition, the findings of the tongue ultrasound can be used to represent the bulbar function. Subjects and methods: Eleven patients with definite ALS; 8 males and 3 females with mean age of 44.55 ± 8.90 years participated in the study. All patients were subjected to bilateral phrenic nerve conduction studies, ultrasound of the diaphragm and ultrasound examination of the tongue. Results: The amplitude of the CMAP of the phrenic nerve was reduced in 54.4% of patients.The diaphragm excursion was abnormal in 9.09% of patients and the respiratory thickening ratio was normal in all patients.This showed a statistically significant difference between phrenic nerve amplitude and diaphragm ultrasound (p value=0.022). The phrenic nerve amplitude was significantly correlated with the revised ALS functional rating scale (ALSFRS-R) respiratory sub-score (p=0.019) while diaphragm ultrasound was not.Tongue echo intensity showed a sensitivity of 63.6%
530 _aIssued also as CD
653 4 _aAmyotrophic lateral sclerosis disease
653 4 _aDiaphragmatic function
653 4 _aPhrenic nerve conduction studies
700 0 _aAmani Mahmoud Nawito ,
_eSupervisor
700 0 _aHanan Helmy Elgendy ,
_eSupervisor
700 0 _aMye Ali Basheer ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c83761
_d83761