000 | 02785cam a2200349 a 4500 | ||
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003 | EG-GiCUC | ||
005 | 20250223032906.0 | ||
008 | 220101s2021 ua dh f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aM.Sc | ||
099 | _aCai01.11.36.M.Sc.2021.Fa.R | ||
100 | 0 | _aFatma Alzahraa Ahmad Alsayed Ali | |
245 | 1 | 0 |
_aRespiratory and bulbar dysfunctions in amyotrophic lateral sclerosis : _bElectrophysiologic and muscle ultrasound assessment / _cFatma Alzahraa Ahmad Alsayed Ali ; Supervised Amani Mahmoud Nawito , Hanan Helmy Elgendy , Mye Ali Basheer |
246 | 1 | 5 |
_aالاختلال فى وظائف التنفس والبلع فى التصلب الجانبى الضمورى : _bتقييم باستخدام الفسيولوجيا الكهربية والموجات الصوتية للعضلات |
260 |
_aCairo : _bFatma Alzahraa Ahmad Alsayed Ali , _c2021 |
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300 |
_a92 P. : _bcharts , facsimiles ; _c25cm |
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502 | _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Neurophysiology | ||
520 | _aBackground: Respiratory and bulbar dysfunctions are the leading causes of death in amyotrophic lateral sclerosis disease (ALS).The function of the diaphragm as the primary muscle of respiration can be assessed by phrenic nerve conduction studies and diaphragm ultrasound. In addition, the findings of the tongue ultrasound can be used to represent the bulbar function. Subjects and methods: Eleven patients with definite ALS; 8 males and 3 females with mean age of 44.55 ± 8.90 years participated in the study. All patients were subjected to bilateral phrenic nerve conduction studies, ultrasound of the diaphragm and ultrasound examination of the tongue. Results: The amplitude of the CMAP of the phrenic nerve was reduced in 54.4% of patients.The diaphragm excursion was abnormal in 9.09% of patients and the respiratory thickening ratio was normal in all patients.This showed a statistically significant difference between phrenic nerve amplitude and diaphragm ultrasound (p value=0.022). The phrenic nerve amplitude was significantly correlated with the revised ALS functional rating scale (ALSFRS-R) respiratory sub-score (p=0.019) while diaphragm ultrasound was not.Tongue echo intensity showed a sensitivity of 63.6% | ||
530 | _aIssued also as CD | ||
653 | 4 | _aAmyotrophic lateral sclerosis disease | |
653 | 4 | _aDiaphragmatic function | |
653 | 4 | _aPhrenic nerve conduction studies | |
700 | 0 |
_aAmani Mahmoud Nawito , _eSupervisor |
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700 | 0 |
_aHanan Helmy Elgendy , _eSupervisor |
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700 | 0 |
_aMye Ali Basheer , _eSupervisor |
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856 | _uhttp://172.23.153.220/th.pdf | ||
905 |
_aNazla _eRevisor |
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905 |
_aShimaa _eCataloger |
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_2ddc _cTH |
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_c83761 _d83761 |