| 000 | 02754nam a2200361 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032925.0 | ||
| 008 | 220228s2021 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
||
| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.11.29.Ph.D.2021.As.R | ||
| 100 | 0 | _aAsmaa Farag Hassan Amer | |
| 245 | 1 | 0 |
_aRole of cannabinoid receptor 1 antagonist (rimonabant) in cardiac dysfunction in experimentally induced schizophrenia in rats / _cAsmaa Farag Hassan Amer ; Supervised Nahed Mahmoud Moussa , Soha Aly Elmorsy , Olfat Gamil Shaker |
| 246 | 1 | 5 | _aدور مستقبلات القنب الهندى 1(مونابانت) في قصور وظائف القلب فى مرض الفصام المحدث تجربيا فى الفئران |
| 260 |
_aCairo : _bAsmaa Farag Hassan Amer , _c2021 |
||
| 300 |
_a190 P. : _bcharts , facsimiles ; _c25cm |
||
| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pharmacology | ||
| 520 | _aMales are more affected than females (1.4:1) and it usually begins at a young age (15{u2013}35 years), lasts long time, causes permanent disability, and has a high mortality rates. (Häfner, 2019) The mortality rate of schizophrenia in patients with mental disorders is 2{u2013}3 times higher than in the general populations with 10{u2013}20 years shorter life expectancy. (Garcia-Rizo & Bitanihirwe, 2020) antipsychotic medications, either typical or atypical, are the mainstay of treatment in addition to case management and social rehabilitation. (D. Siskind, Siskind, & Kisely, 2017) Cardiovascular pathologies are a leading cause of death in patients with schizophrenia whom are reported to have a 3-4 fold increased risk of dying prematurely from cardiovascular disease. (O{u201F}Neill et al., 2020) The rise in cardiovascular mortality has been attributed in part to patients' poor lifestyle choices. The use of antipsychotic drugs, on the other hand, is a major risk factor. (Vohra, 2020) Antipsychotics have been shown to prolong the corrected QT interval and, in some cases, cause sudden cardiac death. (Barcella et al., 2021) Refractory schizophrenic patients are those who do not respond properly to antipsychotic treatment and are classified as 30%{u2013}60% of all schizophrenia patients | ||
| 530 | _aIssued also as CD | ||
| 650 | 0 | _aPharmacology | |
| 653 | _aCardiac dysfunction | ||
| 653 | _aRimonabant | ||
| 653 | _aSchizophrenia | ||
| 700 | 0 |
_aNahed Mahmoud Moussa , _eSupervisor |
|
| 700 | 0 |
_aOlfat Gamil Shaker , _eSupervisor |
|
| 700 | 0 |
_aSoha Aly Elmorsy , _eSupervisor |
|
| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aShimaa _eCataloger |
||
| 905 | _eRevisor | ||
| 942 |
_2ddc _cTH |
||
| 999 |
_c84376 _d84376 |
||