000			02980nam a2200337 a 4500
003			EG-GiCUC
008			220307s2022 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.10.09.M.Sc.2022.Em.C
100	0		_aEman Hamdy Saad Ghallab
245	1	0	_aClinical and laboratory studies on thyroid gland hormones in dogs in health and disease / _cEman Hamdy Saad Ghallab ; Supervised Taher Ahmad Mahmoud Baraka , Hitham Abdelsaeed Mohamed , Haithem Ali Farghali
246	1	5	_aدراسات اكلينيكية ومعملية على هرمونات الغدة الدرقية في الكلاب في الصحة والمرض
260			_aCairo : _bEman Hamdy Saad Ghallab , _c2022
300			_a158 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Internal Medicine Infection Diseases
520			_aTotal number (No.) of 441 dogs was examined during the period of 2018 till 2020. These animals were admitted to a private clinic in Cairo Governorate, Egypt for various clinical manifestations. Of 441 dogs enrolled, only 82 dogs showed a reduction in TT4, 403 affected have features of hypothyroidism and 38 dogs clinically healthy showed no signs of disease consider as control group. Animals were thoroughly examined and clinical signs and epidemiological data include age, sex, season and dog breeds were recorded. Blood samples were collected from the jugular or cephalic vein from each dog in lithium heparin cups or on plain tube for serum separation. Heparinized blood or serum were used to determine TT4 levels using veterinary specific kits (Catalyst total T4 slide) and Catalyst One Chemistry Analyzer, IDEXX laboratories , Inc, Westbrook, Maine, according to the manufacturer{u2019}s instruction, for screening incidence of hypothyroidism in the examined dogs. Data are represented as Mean ± SE, data set was compared using graphpad PRISM, P value < 0.05 considered significant. Hypothyroidism showed higher incidence in middle aged dogs (1-5 years), in males compared to females, in autumn than other seasons, and in large dog breeds.TT4 levels in this study ranged between 0.5-1 og/dl with mean 0.8 ± 0.017. TT4 should be put in consideration during diagnosis of suspected cases related to dermatological, gynecological, otitis, CNS, tumors, dwarfism, cardiac, GIT, low BCS, obesity, eye and mixed signs. Special care should be associated with sharp decrease in TT4 in cases of CNS
530			_aIssued also as CD
650		0	_aHormones
653			_aCanine
653			_aHypothyroidism features
653			_aThyroid hormones
700	0		_aHaithem Ali Farghali , _eSupervisor
700	0		_aHitham Abdelsaeed Mohamed , _eSupervisor
700	0		_aTaher Ahmad Mahmoud Baraka , _eSupervisor
905			_aEnas _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c84424 _d84424