000 03019nam a2200361 a 4500
003 EG-GiCUC
005 20250223032937.0
008 220918s2022 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.10.13.M.Sc.2022.Am.B
100 0 _aAmr Hesham Ahmed
245 1 0 _aBrief on Canine Carpal Arthrodesis :
_b (experimental study) /
_cAmr Hesham Ahmed ; Supervised Faisal Abdelsamad Mohamed Torad , Ashraf Aly Eldesoky Shamaa , Ahmed Ismael Abdelgalil
246 1 5 _aدراسة تجريبية :
_bنبذة عن التمعظم المفصلي لمفصل الرسغ في الكلاب
260 _aCairo :
_bAmr Hesham Ahmed ,
_c2022
300 _a93 P . :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Surgery, Anesthesiology and Radiology
520 _aA novel application of mesenchymal stem cell-derived microvesicles (MSC-derived MVs) with arthrodesis in dogs is described, radiographic osseous union, lameness score, histological findings, and complications following surgery are assessed. This study compared the procedure type in 20 cases of pan carpal arthrodesis in a canine model. 20 apparently healthy mongrel dogs of both sexes, 1 -2 years old were randomly allocated in four main groups; 5 animals for each; Group I: cancellous bone graft group BG (treated with pan carpal arthrodesis and received autologous bone graft) Group II: mesenchymal stem cell-derived microvesicles group MVs (treated with pan carpal arthrodesis and received MSCs derived MVs only) and Group III: mixed group (treated with pan carpal arthrodesis and received cancellous bone graft seeded with MSCs derived MVs). Another group is the control negative group (received nothing). that{u2018}s only treated with pan carpal arthrodesis without receiving any healing enhancement material. Radiographs were reviewed at 4, 8, and 12 weeks after surgery to compare the score of the radiographic osseous union. and the obtained results showed that group 2 (MSCs derived MVs) had a higher radiographic score than other groups followed by the mixed group while the (Bone Graft) and (control) groups show the lowest scoring. The BG group had significantly more major complications that required re-operation for implant removal or treatment of a deep infection compared to the other groups. Overall, mesenchymal stem cell-derived microvesicles may be used to augment arthrodesis in dogs without significant morbidity
530 _aIssued also as CD
650 0 _aarthrodesis
653 _amicrovesicles
653 _apan-carpal,
653 _astem-cells
700 0 _aAhmed Ismael Abdelgalil ,
_eSupervisor
700 0 _aAshraf Aly Eldesoky Shamaa ,
_eSupervisor
700 0 _aFaisal Abdelsamad Mohamed Torad ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAmira
_eCataloger
905 _eRevisor
942 _2ddc
_cTH
999 _c84806
_d84806