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Synthesis of certain fused thienopyridine derivatives of expected activity against alzheimer's disease / Afaf Ali Atia Elmalah ; Supervised Mohga Mohamed Badran , Maha Abdelhakeem , Suzan Mohamed Abuelmaaty

By: Contributor(s): Material type: TextLanguage: English Publication details: Cairo : Afaf Ali Atia Elmalah , 2010Description: 120P. : facsimiles ; 25cmOther title:
  • تشييد بعض مركبات الثاينوبيريدين الملتحمة ذات نشاط متوقع ضد مرض الالزهيمر [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry Summary: A survey covering the methods used for the synthesis of thienopyridine derivatives in addition to their reactions is illustrated . Abrief outline on their medical importance is also given . This thesis involves the preparation of the starting compounds 2- amino - 3- cyanothiophene derivatives {u2161}a-c (scheme 1) . cyclodehydration reaction between the aminocyanothiophenes and the appropriate cyclanone was achieved by using two methods to obtain thienopyridine derivatives {u2162}a-c, IVa-c, {u2164}a-c, {u2165}I, {u2167} and IX(scheme 2- 4)
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Item type Current library Home library Call number Copy number Status Barcode
Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.04.Ph.D.2010.Af.S (Browse shelf(Opens below)) Not for loan 01010110054594000
CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.04.Ph.D.2010.Af.S (Browse shelf(Opens below)) 54594.CD Not for loan 01020110054594000

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry

A survey covering the methods used for the synthesis of thienopyridine derivatives in addition to their reactions is illustrated . Abrief outline on their medical importance is also given . This thesis involves the preparation of the starting compounds 2- amino - 3- cyanothiophene derivatives {u2161}a-c (scheme 1) . cyclodehydration reaction between the aminocyanothiophenes and the appropriate cyclanone was achieved by using two methods to obtain thienopyridine derivatives {u2162}a-c, IVa-c, {u2164}a-c, {u2165}I, {u2167} and IX(scheme 2- 4)

Issued also as CD

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