Characterization and in vitro differentiation of bone marrow stem cells into hepatocytes / Asmaa Ahmed Elsayed Osman ; Supervised Nesrine Mohamed Elgharbawi , Doaa Atef Soliman , Reham A. Aleem Afefy

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Asmaa Ahmed Elsayed Osman

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TextLanguage: English Publication details: Cairo : Asmaa Ahmed Elsayed Osman , 2014Description: 174 P. : charts , facsimiles ; 25cmOther title:

دراسة صفات الخلايا الكبدية المخلقة خارج الجسم من خلايا النخاع الشوكي [Added title page title]

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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology Summary: Background: Orthotopic liver transplantation is the only definitive therapeutic option available for patients with chronic end-stage liver disease. However, a shortage of suitable donor organs and requirement for immunosuppression restrict its usage, highlighting the need to find suitable alternatives. Stem cell therapy has emerged as a novel approach for the treatment of many human degenerative diseases such as liver cirrhosis. Mesenchymal stem cells (MSC) have the capacity of self-renewal and differentiation into cells of various lineages, MSCs are the most potent component of bone marrow cells in hepatic dif»feren»tiation so they can be isolated from bone marrow (BM) and induced to differentiate into hepatocyte-like cells

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Item type	Current library	Home library	Call number	Copy number	Status	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.07.Ph.D.2014.As.C (Browse shelf(Opens below))		Not for loan	01010110064249000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.07.Ph.D.2014.As.C (Browse shelf(Opens below))	64249.CD	Not for loan	01020110064249000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Background: Orthotopic liver transplantation is the only definitive therapeutic option available for patients with chronic end-stage liver disease. However, a shortage of suitable donor organs and requirement for immunosuppression restrict its usage, highlighting the need to find suitable alternatives. Stem cell therapy has emerged as a novel approach for the treatment of many human degenerative diseases such as liver cirrhosis. Mesenchymal stem cells (MSC) have the capacity of self-renewal and differentiation into cells of various lineages, MSCs are the most potent component of bone marrow cells in hepatic dif»feren»tiation so they can be isolated from bone marrow (BM) and induced to differentiate into hepatocyte-like cells

Issued also as CD

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