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Study on the possible hepatoprotive effect of certain drugs against ischemia/reperfusion liver injury in rats / Abdallah Mohammed Said Ahmed Gendy ; Supervised Hanan Salaheldin Elabhar , Rania Mohsen Abdelsalam

By: Contributor(s): Material type: TextLanguage: English Publication details: Cairo : Abdallah Mohammed Said Ahmed Gendy , 2014Description: 167 P. : charts ; 25cmOther title:
  • التأثير الكبدى الوقائى المحتمل لبعض الأدوية ضد الدم فى كبد الجرزان المتبوع بإعادة التروية [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology Summary: Cilostazol is an antiplatelet that acts by inhibiting phosphodiesterase-3 and that was proven to be effective in models of ischemia/reperfusion (I/R) injury; however, its possible role in hepatic 1/R remains indistinct, which is the aim of the current work. cilostazol potential effect was compared to known ani-ischemic drug trimetazidine, which is used as an antianginal drug and that protects heart and liver against 1/R. to fulfill the goal, rats were randomized into sham, 1/R, cilostazol (60mg/Kg, p.o) and trimetazidine (20mg/kg, p.o) groups
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Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.09.M.Sc.2014.Ab.S (Browse shelf(Opens below)) Not for loan 01010110064673000
CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.09.M.Sc.2014.Ab.S (Browse shelf(Opens below)) 64673.CD Not for loan 01020110064673000

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology

Cilostazol is an antiplatelet that acts by inhibiting phosphodiesterase-3 and that was proven to be effective in models of ischemia/reperfusion (I/R) injury; however, its possible role in hepatic 1/R remains indistinct, which is the aim of the current work. cilostazol potential effect was compared to known ani-ischemic drug trimetazidine, which is used as an antianginal drug and that protects heart and liver against 1/R. to fulfill the goal, rats were randomized into sham, 1/R, cilostazol (60mg/Kg, p.o) and trimetazidine (20mg/kg, p.o) groups

Issued also as CD

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