Thesis (Ph.D.) - Cairo University - Faculty of Physical Therapy - Department of Physical Therapy for Cardiopulmonary and Geriatric Disorders

Background: Coronary artery disease (CAD) is the most common cause of death in the developed world, responsible for about 1 in every 5 deaths and it is expected that its rate will accelerate in the next decade. Purpose: To find out adipokines response to continuous versus interval aerobic training in ischaemic heart disease patients. Patients and method: Forty men patients with an ischemic heart disease with age ranged from 50-60 years old participated in this study. They were recruited from cardiac outpatient clinic of Kasr Elainy hospital. Patients were assigned into two groups equal in number: Group A included 20 patients received high intensity interval aerobic training on treadmill 3 times/week for 12 weeks. Group B included 20 patients received moderate intensity continuous aerobic training on treadmill 3 times/week for 12 weeks. Serum adiponectin, serum leptin, 6 minute walk distance and patient{u2019}s specific quality of life were measured before and after training program for both groups. Results: Statistical analysis revealed that high intensity interval aerobic training has more significant effect on serum adiponectin (28.25%{u2191}), serum leptin (9.19%{u2193}), 6 minute walk distance (16.55%{u2191}) and patient{u2019}s specific quality of life median (88.8) (75) (80) than moderate intensity continuous aerobic training (14.33%{u2191}), (4.67%{u2193}), (10.37%{u2191}) and (66.6), (66.6), (67.5) respectively. Conclusion: High intensity interval appears to be more effective than moderate intensity continuous aerobic training for improvement of adipokines, functional capacity and quality of life in patients with ischemic heart disease

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