Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Surgery

Objectives: This study was conducted to compare between the effect non-invasive treatment modality using fluoride, Tri-Calcium Phosphate and nanohydroxyapatite based remineralizing agents versus micro-invasive treatment modality using Resinous and Resin modified glass ionomer Infiltrants materials on surface micro-hardness of incipient carious enamel lesions. Furthermore, the stability of these treatment options upon exposure to acidic challenge. Methods: A total of 60 sound human permanent molars were used in this study. The specimens were divided into six equal groups (10 teeth for each group) according to the treatment modality; Group (A0): Artificial saliva, Group (A1): fluoride, Group (A2): Tri-Calcium Phosphate, Group (A3): Nano Hydroxyapatite, Group (A4): Resin infiltrant and Group (A5): Resin modified glass ionomer infiltrant. The molars were decoronated and mounted in cylindrical self-cured acrylic resin molds with their buccal surface facing upwards. The buccal surface of each molar was polished using 400,600,800 and 1200 grit silicon carbide abrasive papers. A standardized window of 5mm {u00D7} 3mm dimension was created on the buccal enamel surface of each specimen which demarcated by acid resistant nail varnish of different colors. To induce incipient carious enamel lesions, specimens were immersed in demineralizing solution at pH45 for 72 hours at room temperatureAll treatments were applied according to the manufacturers{u2019} instructions. After application of the tested materials, all specimens were immersed in artificial saliva for two weeks.The specimens were finally subjected to acidic challenge using the same demineralizing protocol used for inducing caries-like lesions

Issued also as CD