Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Gynaecology and Obstetrics

Objective : To investigate the correlation between BMI and endometrial thickness and to assess the accuracy of endometrial thickness measurement by transvaginal ultrasound in the diagnosis of endometrial pathology in asymptomatic obese and non-obese postmenopausal women . Design : Cross sectional analytic study. Setting : Kasr El-Aini Hospital Patients and Methods: 120 asymptomatic postmenopausal women ( without vaginal bleeding) , recruited from the Outpatient Gynecology Clinic, Kasr Al-Ainy Hospital, were included in the study. All patients were subjected to measurement of Body Mass Index (BMI) then they were assigned to two groups according to BMI ( non-obese <30 and obese {u2265}30 ) and 2-dimensional transvaginal ultrasonographic evaluation of the endometrium of all patients was done. The endometrial thickness of all patients was correlated to BMI and to the histopathological picture of the endometrium of the patients with thickened endometrium {u2265}5mm Results: In obese group the endometrial thickness((mean ± SD) was(5.97±4.75 mm) and (3.37±2.74mm) in non-obese group with P value (< 0.001) . There were 27 cases with thick endometrium;7 cases were non obese (5.8%) & 20 cases were obese (16.7%) . It was found that patients with thick endometrium had higher BMI than patients with thin endometrium P value (< 0.001).The histopathological results of the thickened endometrium (27 cases) were : Polyp (29.6%), Proliferative endometrium (25.9%) , Simple endometrial hyperplasia without atypia (22.2%), Atrophic endometrium (7.4%), Simple endometrial hyperplasia with atypia (7.4%), Secretory (3.7%), Carcinoma (3.7%)

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