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Expression of JAK2 V617F mutation in chronic myeloproliferative disorders /

Gehan Hamed Shahin

Expression of JAK2 V617F mutation in chronic myeloproliferative disorders / التعبير عن طفرة جاك 2 فى 617 اف فى امراض التكاثر الميلويدى المزمن Gehan Hamed Shahin ; Supervised Sherif Nasseh Amin , Samah Mohamed Abdelhameed , Manal Mohamed Mahmoud Makhlouf - Cairo : Gehan Hamed Shahin , 2008 - 181P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology

JAK2 is a non receptor tyrosine kinase that plays a major role in myeloid development by transducing signals from diverse cytokines and growth factor receptors a mutation in this janus kinase interferes with the negative regulation of JAK2 and could account for the hypersensitivity of myeloid cells from MPD patients to growth factors



CMPDs patients JAK2 V617F MPD
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