Gene expression analysis of BCRP in bladder cancer /

Mona Ahmed Hassan Rady

Gene expression analysis of BCRP in bladder cancer / Mona Ahmed Hassan Rady ; Supervised Hilde Spahn-Langguth , Jan Rohde , Marwa Mostageer - Cairo : Mona Ahmed Hassan Rady , 2009 - 90 Leaves : charts ; 30cm

Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and Toxicology

The breast cancer resistance protein (BCRP) is an ATP - binding cassete (ABC) membrane efflux transporter . First identified from drug - resistant cancer cell lines, BCRP was shown to contribute to multidrug resistance (MDR) in vitro . Bioloically , BCRP functions as a cytoprotectant extruding endogenous and exogenous toxic substances out of cells
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