The role of CD86 and vascular endothelial growth factor in acute myeloid leukemia /

Rania Salah Abdelaziz

The role of CD86 and vascular endothelial growth factor in acute myeloid leukemia / دور سى دى 86 وعامل النشوء الوعائى الدموى فى سرطان الدم الميلودى الحاد Rania Salah Abdelaziz ; Supervised Magda M. A. Assem , Basma M. Elgamal , Sherine I. Salem - Cairo : Rania Salah Abdelaziz , 2009 - 212P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology

AML is the most frequent type of leukemia in adult . Recognition and destruction of leukemic blasts by the immune system is of great interest for the development of immuntherapeutic strategies in AML . T- cell activation requires T-cell receptor recognition and binding to major histocompatability complex (MHC) complex/angtigen presented by an antigen-presenting cell (APC) and the binding of ligands for the T - cell costimulatory receptors CD28 and CTLA - 4, ie, CD80/B7 - 1 and CD86/B7 - 2, respectively



CD80 CD86 Vasclar Endothelial Growth Factor
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