The association between kir6.2 mutation and type 1 diabetes /
Alaa Afif Abdelraouf
The association between kir6.2 mutation and type 1 diabetes / العلاقة بين التحور الجينى للجين ( كير 2و6 ) والنوع الاول من البول السكرى Alaa Afif Abdelraouf ; Supervised Nadida Abdelhamid Gohar , Shereen Abdelghaffar Taha , Nahla Aly Fawzy Fayek - Cairo : Alaa Afif Abdelraouf , 2012 - 81Leaves : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
The pancreatic ATP - sensitive potassium ( Katp ) channel is a critical regulator of beta - cell insulin secretion . Heterozygous activating mutations in the KCNJ11 gene , which encodes the Kir 6.2 subunit of the Katp channel , have been found to cause diabetes in the neonatal period or early infancy . This molecular study hypothesized that KCNJ11 mutations could present clinically as type 1 diabetes
Katp channel kir6.2 Neonatal diabetes
The association between kir6.2 mutation and type 1 diabetes / العلاقة بين التحور الجينى للجين ( كير 2و6 ) والنوع الاول من البول السكرى Alaa Afif Abdelraouf ; Supervised Nadida Abdelhamid Gohar , Shereen Abdelghaffar Taha , Nahla Aly Fawzy Fayek - Cairo : Alaa Afif Abdelraouf , 2012 - 81Leaves : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
The pancreatic ATP - sensitive potassium ( Katp ) channel is a critical regulator of beta - cell insulin secretion . Heterozygous activating mutations in the KCNJ11 gene , which encodes the Kir 6.2 subunit of the Katp channel , have been found to cause diabetes in the neonatal period or early infancy . This molecular study hypothesized that KCNJ11 mutations could present clinically as type 1 diabetes
Katp channel kir6.2 Neonatal diabetes