Physical properties and pharmaceutical applications of chitosan nanoparticles loaded with hydrophobic drugs /

Sally Tarek Elbanna

Physical properties and pharmaceutical applications of chitosan nanoparticles loaded with hydrophobic drugs / الخواص الفيزيقية والتطبيقات الصيدلانية لحبيبات نانومترية من الكيتوزان محملة بأدوية كارهة للماء Sally Tarek Elbanna ; Supervised Wafaa A. Khalil , Safaa K. H. Khalil - Cairo : Sally Tarek Elbanna , 2012 - 142P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biophysics

Chitosan nanoparticles were successfully prepared by ionic gelation method . They were loaded with a hydrophobic drug model , warfarin , in order to enhance its bioavailability and controlled release in blood circulation system . To overcome the hydrophobic nature of warfarin , it was complexed with Ý- cyclodextrin . The drug loaded nanoparticles were characterized by SEM , TEM , Zeta potential , FT - IR and UV - visible spectroscopy



Chitosan nanoparticles Controlled release Ionic gelation
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