A pharmaceutical study on controlled release baclofen tablets /

Ibrahim Ahmed Elsaid Mohamed

A pharmaceutical study on controlled release baclofen tablets / دراسة صيدلية على أقراص منضبطة الإنطلاق لعقار الباكلوفين Ibrahim A. Elsaid ; Supervised Omaima N. Elgazayerly , Rawia M. Khalil , Ahmed A. Aboelwafa - Cairo : Ibrahim Ahmed Elsaid Mohamed , 2012 - 245P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics

The main goal of this work is to formulate gastroretentive dosage forms capable of increasing the residence of baclofen at its absorption window and modifying oral baclofen release , in an attempt to counteract the low plasma elimination half - life of baclofen (3 to 4 hours) , minimize dose fluctuation and improve therapeutic response for patients suffering from spasticity and chronic musculoskeletal conditions



Baclofen Gastroretentive Superporous
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