One pot synthesis and biological evaluation of novel heterocyclic compounds /
Aya Mohamed Abdelkader Serry
One pot synthesis and biological evaluation of novel heterocyclic compounds / التشييد والتقييم البيولوجى لمركبات جديدة غير متجانسة الحلقة Aya Mohamed Abdelkader Serry ; Supervised Ashraf H. Abadi - Cairo : Aya Mohamed Abdelkader Serry , 2009 - 98Leaves : charts ; 30cm
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
P38Ü mitogen activated protein kinase regulates the expression of inflammatory cytokines suggesting a role in the pathogenesis of diseases such as rheumatoid arthritis as well as cancer progression . Many heterocyclic compouds have been reported to posses p38 MAP kinase inhibitory properties however the main shortcoming for development into clinical candidates were toxicity and unselectivity towards other kinases
One pot synthesis and biological evaluation of novel heterocyclic compounds / التشييد والتقييم البيولوجى لمركبات جديدة غير متجانسة الحلقة Aya Mohamed Abdelkader Serry ; Supervised Ashraf H. Abadi - Cairo : Aya Mohamed Abdelkader Serry , 2009 - 98Leaves : charts ; 30cm
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
P38Ü mitogen activated protein kinase regulates the expression of inflammatory cytokines suggesting a role in the pathogenesis of diseases such as rheumatoid arthritis as well as cancer progression . Many heterocyclic compouds have been reported to posses p38 MAP kinase inhibitory properties however the main shortcoming for development into clinical candidates were toxicity and unselectivity towards other kinases