Synthesis of novel diary I heterocycle derivatives and their evaluation as growth inhibitory agents and phosphodiesterase 3 inhibitors /
Shaimaa Awadain Elsharif
Synthesis of novel diary I heterocycle derivatives and their evaluation as growth inhibitory agents and phosphodiesterase 3 inhibitors / تشييد مشتقات جديدة لثنائى ارايل غير متجانس الحلقة وتقيم قدرتهم كمثبطات النمو ومنع نشاط الفوسفوداى استراز 3 Shaimaa Awadain Elsharif ; Supervised Ashraf H. Abadi - Cairo : Shaimaa Awadain Elsharif , 2010 - 90Leaves : charts , facsimiles ; 30cm
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical chemistry
Milrinone is a cyanopyridone derivative that has been introduced for the treatment of CHF . Its mechanism of action involves inhibition of PDE3 leading to elevation of cAMP increasing the entry of Ca⁺⁺ ions into the cardiac tissues and hence increasing the contractility of the cardiac muscle
Synthesis of novel diary I heterocycle derivatives and their evaluation as growth inhibitory agents and phosphodiesterase 3 inhibitors / تشييد مشتقات جديدة لثنائى ارايل غير متجانس الحلقة وتقيم قدرتهم كمثبطات النمو ومنع نشاط الفوسفوداى استراز 3 Shaimaa Awadain Elsharif ; Supervised Ashraf H. Abadi - Cairo : Shaimaa Awadain Elsharif , 2010 - 90Leaves : charts , facsimiles ; 30cm
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical chemistry
Milrinone is a cyanopyridone derivative that has been introduced for the treatment of CHF . Its mechanism of action involves inhibition of PDE3 leading to elevation of cAMP increasing the entry of Ca⁺⁺ ions into the cardiac tissues and hence increasing the contractility of the cardiac muscle