Assessment of anti-schistosomal activity of mefloquine, in experimental schistosoma mansoni infection /
Hebat Allah Salah Ahmad Yousuf
Assessment of anti-schistosomal activity of mefloquine, in experimental schistosoma mansoni infection / تقييم مدى فاعلية الميفلوكين على العدوى التجريبيه بالبلهارسيا المعويه Hebat Allah Salah Ahmad Yousuf ; Supervised Omaima Mohammed Aboushady , Soheir Sayed Mohammed Mahmoud , Dina Omar Helmy - Cairo : Hebat Allah Salah Ahmad Yousuf , 2012 - 160 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Parasitology
It has been recently documented that the antimalarial drug mefloquine (MFQ) had interesting anti-schistosomal properties. This study aimed to assess the effect of single oral dose of mefloquine (400 mg/kg) and single oral dose of mefloquine (200 mg/kg) combined with praziquantel (500 mg/kg) on experimental Schistosoma mansoni infection. Mefloquine significantly reduced the worm burden, tissue egg load, number of liver granulomas and increased the percent of the dead ova within the granulomas
Mefloquine Praziquantel S. mansoni
Assessment of anti-schistosomal activity of mefloquine, in experimental schistosoma mansoni infection / تقييم مدى فاعلية الميفلوكين على العدوى التجريبيه بالبلهارسيا المعويه Hebat Allah Salah Ahmad Yousuf ; Supervised Omaima Mohammed Aboushady , Soheir Sayed Mohammed Mahmoud , Dina Omar Helmy - Cairo : Hebat Allah Salah Ahmad Yousuf , 2012 - 160 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Parasitology
It has been recently documented that the antimalarial drug mefloquine (MFQ) had interesting anti-schistosomal properties. This study aimed to assess the effect of single oral dose of mefloquine (400 mg/kg) and single oral dose of mefloquine (200 mg/kg) combined with praziquantel (500 mg/kg) on experimental Schistosoma mansoni infection. Mefloquine significantly reduced the worm burden, tissue egg load, number of liver granulomas and increased the percent of the dead ova within the granulomas
Mefloquine Praziquantel S. mansoni