Pharmacological study on the effect of vitamin E succinate and doxorubicin in experimental animals /

Samar Mohammed Suliman Ibrahim

Pharmacological study on the effect of vitamin E succinate and doxorubicin in experimental animals / الدراسة الدوائية لتاثير سكسينات فيتامين هـ والدوكسوروبيسين عند اعطائهم لحيوانات التجارب Samar Mohammed Suliman Ibrahim ; Supervised Dalaal M. Abdallah , Samia A. Shouman , Hafez Farouk - Cairo : Samar Mohammed Suliman Ibrahim , 2013 - 106 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology

Doxorubicin (DXR) is widely used in the treatment of many human cancers but unfortunately it causes various toxic effects and a significant number of patients develop resistance . Vitamin E succinate (VES) redox - silent analogue of vitamin E is a promising anti- cancer agent . The present study aimed to examine the combined effect of VES and DXR regarding toxicity and antitumor activity in animals



Doxorubicin Tissue homogenate Vitamin E succinate
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