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Expression and prognostic significance of the homeobox gene CDX2 in pediatric acute lymphpblastic leukemia /

Shereen Aly Omar Foad Alkashef

Expression and prognostic significance of the homeobox gene CDX2 in pediatric acute lymphpblastic leukemia / التعبير و التأثير المنذر لجين هوميوبوكس سى دى اكس٢ فى سرطان الدم الليمفاوى الحاد فى الأطفال Shereen Aly Omar Foad Alkashef ; Supervised Hanaa Hamed Arnaoaut , Doha Abdalhamid Mokhtar , Rania Mohamed Samy - Cairo : Shereen Aly Omar Foad Alkashef , 2013 - 182 P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

CDX genes are classically known as regulators of axial elongation during early embryogenesis. An unsuspected role for CDX genes have been revealed during hematopoietic development. The CDX gene family member CDX belongs to the most frequent aberrantly expressed protooncogenes in human acute leukemias and is highly leukemogenic in experimental models



Acute lymphoblastic leukemia Chemical pathology Homeobox gene CDX2
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