Modulating the activity of pyrazoline and pyrazole analogues of celecoxib between phosphodiesterase 5 and cyclooxygenase inhibition /

Mennat Allah Ahmed Hammam Bedair

Modulating the activity of pyrazoline and pyrazole analogues of celecoxib between phosphodiesterase 5 and cyclooxygenase inhibition / تحوير النشاط التثبيطى لمشتقات السيليكوكسيب بين إنزيمى الفوسفودايستراز٥ و الكوكس Mennat Allah Ahmed Hammam Bedair ; Supervised Ashraf H. Abadi - Cairo : Mennat Allah Ahmed Hammam Bedair , 2012 - 101 Leaves : photographs ; 30cm

Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry

Non steroidal anti - inflammatory drugs are among the most widely prescribed drugs all over the world due to their anti - inflammatory, antipyretic and analgesic effects. However, their use has been associated with serious gastromtestinal side effects that were found to be reduced upon the use of selective COX - 2 inhibitors which are collectively called coxibs
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