Formulation of an anti - inflammatory drug as fast dissolving tablets /
Maram Mourad Hassan Mansour
Formulation of an anti - inflammatory drug as fast dissolving tablets / صاغة أقراص سرعة الذوبان بالفم لعقار مضاد للالتھابات Maram Mourad Hassan Mansour ; Supervised Magdy Ibrahim Mohammed , Boushra Mohammed Elhoussieny Yousef - Cairo : Maram Mourad Hassan Mansour , 2014 - 189 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics
Ketorolac tromethamine is a potent non steroidal anti - inflammatory drug (NSAID) that is widely used in treatment of moderate to sever pain. It was reported that ketorolac produces its analgesic activity via inhibition of prostaglandin synthesis. However, due to its high potency, it has been proposed that this drug has another mechanism of action such as nitric oxide release. ketorolac tromethamine fast dissolving tablets were developed using direct compression method with the addition of superdisintegrants. Three types of superdisintegrants namely croscaramellose sodium, crospovidone and sodium starch glycolate were incorporated in tablets formulation
Direct compression Fast dissolving tablets Ketroloac tromethamine
Formulation of an anti - inflammatory drug as fast dissolving tablets / صاغة أقراص سرعة الذوبان بالفم لعقار مضاد للالتھابات Maram Mourad Hassan Mansour ; Supervised Magdy Ibrahim Mohammed , Boushra Mohammed Elhoussieny Yousef - Cairo : Maram Mourad Hassan Mansour , 2014 - 189 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics
Ketorolac tromethamine is a potent non steroidal anti - inflammatory drug (NSAID) that is widely used in treatment of moderate to sever pain. It was reported that ketorolac produces its analgesic activity via inhibition of prostaglandin synthesis. However, due to its high potency, it has been proposed that this drug has another mechanism of action such as nitric oxide release. ketorolac tromethamine fast dissolving tablets were developed using direct compression method with the addition of superdisintegrants. Three types of superdisintegrants namely croscaramellose sodium, crospovidone and sodium starch glycolate were incorporated in tablets formulation
Direct compression Fast dissolving tablets Ketroloac tromethamine