Association of platelet endothelial cell adhesion molecule - 1 (PECAM -1) gene polymorphisms with coronary artery disease /
Heba Mohamed Amer
Association of platelet endothelial cell adhesion molecule - 1 (PECAM -1) gene polymorphisms with coronary artery disease / بمرض شرايين القلب التاجية (PECAM-1) ارتباط التغير الشكلى لجينات جزيئات المركب الملتصق بالخلايا البطانية و الصفائح الدموية Heba Mohamed Amer ; Supervised Laila Abdelrahman Hegazy , Hassan Mohamed Khalid , Asmaa Ahmed Abdelaal - Cairo : Heba Mohamed Amer , 2014 - 130 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
Platelet endothelial cell adhesion molecule -1 (PECAM - 1) plays a key role in the transendothelial migration of circulating leukocytes, a characteristic event in vascular inflammation leading to atherosclerotic plaque formation. The aim of the present study was to determine the role of PECAM - 1 in the development of coronary artery disease (CAD). Two single nucleotide polymorphisms (SNPs) of PECAM - 1 gene: C + 373G (Leu125Val) at exon 3 and G + 1688A (Ser563Asn) at exon 8 were analyzed in 50 angiographically documented ( > 70% stenosis) Egyptian patients with CAD and 40 age- and sex-matched controls using a polymerase chain reaction -restriction fragment length polymorphism PCR - RFLP strategy
Coronary artery disease Gene polymorphism PECAM - 1
Association of platelet endothelial cell adhesion molecule - 1 (PECAM -1) gene polymorphisms with coronary artery disease / بمرض شرايين القلب التاجية (PECAM-1) ارتباط التغير الشكلى لجينات جزيئات المركب الملتصق بالخلايا البطانية و الصفائح الدموية Heba Mohamed Amer ; Supervised Laila Abdelrahman Hegazy , Hassan Mohamed Khalid , Asmaa Ahmed Abdelaal - Cairo : Heba Mohamed Amer , 2014 - 130 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
Platelet endothelial cell adhesion molecule -1 (PECAM - 1) plays a key role in the transendothelial migration of circulating leukocytes, a characteristic event in vascular inflammation leading to atherosclerotic plaque formation. The aim of the present study was to determine the role of PECAM - 1 in the development of coronary artery disease (CAD). Two single nucleotide polymorphisms (SNPs) of PECAM - 1 gene: C + 373G (Leu125Val) at exon 3 and G + 1688A (Ser563Asn) at exon 8 were analyzed in 50 angiographically documented ( > 70% stenosis) Egyptian patients with CAD and 40 age- and sex-matched controls using a polymerase chain reaction -restriction fragment length polymorphism PCR - RFLP strategy
Coronary artery disease Gene polymorphism PECAM - 1